Detailed Information on Publication Record
2023
Brain Areas Predisposing to the Stroke-Related Epilepsy Development
WEISS, Viktor, Pavel ŘÍHA, Irena DOLEŽALOVÁ, Martin KOJAN, Vladimír ČERVEŇÁK et. al.Basic information
Original name
Brain Areas Predisposing to the Stroke-Related Epilepsy Development
Authors
WEISS, Viktor (203 Czech Republic, belonging to the institution), Pavel ŘÍHA (203 Czech Republic, belonging to the institution), Irena DOLEŽALOVÁ (203 Czech Republic, belonging to the institution), Martin KOJAN (703 Slovakia, belonging to the institution), Vladimír ČERVEŇÁK (203 Czech Republic, belonging to the institution), Julius SIMKO (203 Czech Republic), Roman HERZIG (203 Czech Republic) and Ivan REKTOR (203 Czech Republic, guarantor, belonging to the institution)
Edition
Acta Neurologica Scandinavica, MALDEN, WILEY-BLACKWELL, 2023, 0001-6314
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30210 Clinical neurology
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 3.500 in 2022
RIV identification code
RIV/00216224:14110/23:00134674
Organization unit
Faculty of Medicine
UT WoS
001057498800001
Keywords in English
stroke-related epilepsy; brain; ischemia;
Tags
International impact, Reviewed
Změněno: 15/2/2024 21:37, Mgr. Eva Dubská
Abstract
V originále
Background. Stroke-related epilepsy (STRE) represents a significant health problem. We focused on identifying brain areas, which involvement in ischemia predisposes a patient to STRE development. Methods. We retrospectively identified a group of patients with STRE consisting of 33 subjects. Subsequently, age-, sex-, and territory-matched controls who underwent stroke but did not develop STRE (control group (CG)) were identified. The CG was composed of 37 patients. The total ischemia volume and distribution of ischemic changes were compared between STRE and CG. We also analyzed multivariate statistics to identify independent variables predisposing to STRE development. Results. The patients with STRE exhibited a bigger volume of ischemia than CG (average volume of ischemia in STRE 60.8 cm3, in CG 42.4 cm3, p=0.029). When comparing STRE and CG, there were differences in the distribution of ischemic changes in the temporal lobe (transverse (Heschl's) temporal gyri, superior temporal gyrus, and middle temporal gyrus) and parietooccipital region (postcentral gyrus, supramarginal gyrus, angular gyrus, parietal operculum, lingual gyrus, and superior occipital gyrus). The involvement of transverse temporal (Heschl's) gyri (p=0.0222, odds ratio 30.0767), age (p=0.0110, odds ratio 1.0745), and SeLECT score (p=0.0480, odds ratio 1.8682) were identified as independent predictors for STRE development. Conclusion. The higher volume of ischemia correlates with a higher risk of STRE development. Some areas, particularly in the temporal and parietal neocortex, predispose the brain to generate epilepsy after the stroke.
Links
| NU21-04-00254, research and development project |
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