| KUCHYNKA, Michaela, Hana HOLCOVÁ POLANSKÁ, Jaromír GUMULEC, Viktor KANICKÝ and Tomáš VACULOVIČ. Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory. Journal of Chemical Education. WASHINGTON: American Chemical Society, 2023, vol. 100, No 5, p. 1973-1979. ISSN 0021-9584. Available from: https://dx.doi.org/10.1021/acs.jchemed.2c01111. |
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@article{2341300,
author = {Kuchynka, Michaela and Holcová Polanská, Hana and Gumulec, Jaromír and Kanický, Viktor and Vaculovič, Tomáš},
article_location = {WASHINGTON},
article_number = {5},
doi = {http://dx.doi.org/10.1021/acs.jchemed.2c01111},
keywords = {Upper-Division Undergraduate; Analytical Chemistry; Lasers; Mass Spectrometry; Quantitative Analysis},
language = {eng},
issn = {0021-9584},
journal = {Journal of Chemical Education},
title = {Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory},
url = {https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01111},
volume = {100},
year = {2023}
}
TY - JOUR
ID - 2341300
AU - Kuchynka, Michaela - Holcová Polanská, Hana - Gumulec, Jaromír - Kanický, Viktor - Vaculovič, Tomáš
PY - 2023
TI - Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory
JF - Journal of Chemical Education
VL - 100
IS - 5
SP - 1973-1979
EP - 1973-1979
PB - American Chemical Society
SN - 00219584
KW - Upper-Division Undergraduate
KW - Analytical Chemistry
KW - Lasers
KW - Mass Spectrometry
KW - Quantitative Analysis
UR - https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01111
N2 - A new experiment using laser ablation with inductively coupled plasma mass spectrometry (LA-ICP-MS) was designed for chemistry undergraduate students. While most analytical methods only provide information on the amount of the analyte, LA-ICP-MS allows extra information on the distribution of the element in the sample. Because it achieves excellent limits of detection (sub mu g center dot g-1) and high spatial resolution (micrometer scale), it is a powerful technique for imaging any sample. A thin section of mouse tissue was used as a model sample to demonstrate these abilities. The student's task was to determine the distribution of the essential elements Zn, Cu, and Pt (Pt introduced into the tumor tissue from the cytostatic drug (cis Pt)) and quantify their amount.
ER -
KUCHYNKA, Michaela, Hana HOLCOVÁ POLANSKÁ, Jaromír GUMULEC, Viktor KANICKÝ and Tomáš VACULOVIČ. Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory. \textit{Journal of Chemical Education}. WASHINGTON: American Chemical Society, 2023, vol.~100, No~5, p.~1973-1979. ISSN~0021-9584. Available from: https://dx.doi.org/10.1021/acs.jchemed.2c01111.
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