Detailed Information on Publication Record
2023
Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory
KUCHYNKA, Michaela, Hana HOLCOVÁ POLANSKÁ, Jaromír GUMULEC, Viktor KANICKÝ, Tomáš VACULOVIČ et. al.Basic information
Original name
Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory
Authors
KUCHYNKA, Michaela (203 Czech Republic, guarantor, belonging to the institution), Hana HOLCOVÁ POLANSKÁ (203 Czech Republic, belonging to the institution), Jaromír GUMULEC (203 Czech Republic, belonging to the institution), Viktor KANICKÝ (203 Czech Republic, belonging to the institution) and Tomáš VACULOVIČ (203 Czech Republic, belonging to the institution)
Edition
Journal of Chemical Education, WASHINGTON, American Chemical Society, 2023, 0021-9584
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30104 Pharmacology and pharmacy
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 3.000 in 2022
RIV identification code
RIV/00216224:14310/23:00132316
Organization unit
Faculty of Science
UT WoS
000979469700001
Keywords in English
Upper-Division Undergraduate; Analytical Chemistry; Lasers; Mass Spectrometry; Quantitative Analysis
Tags
International impact, Reviewed
Změněno: 18/3/2024 16:06, Mgr. Marie Šípková, DiS.
Abstract
V originále
A new experiment using laser ablation with inductively coupled plasma mass spectrometry (LA-ICP-MS) was designed for chemistry undergraduate students. While most analytical methods only provide information on the amount of the analyte, LA-ICP-MS allows extra information on the distribution of the element in the sample. Because it achieves excellent limits of detection (sub mu g center dot g-1) and high spatial resolution (micrometer scale), it is a powerful technique for imaging any sample. A thin section of mouse tissue was used as a model sample to demonstrate these abilities. The student's task was to determine the distribution of the essential elements Zn, Cu, and Pt (Pt introduced into the tumor tissue from the cytostatic drug (cis Pt)) and quantify their amount.
Links
MUNI/R/1568/2020, interní kód MU |
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