Detailed Information on Publication Record
2023
FASTER THROMBOLYSIS IN VIVO
BRHELOVÁ, Eliška, Radka OPATŘILOVÁ, Peter SCHEER, Jana HLOŽKOVÁ, Sandra THALEROVÁ et. al.Basic information
Original name
FASTER THROMBOLYSIS IN VIVO
Authors
BRHELOVÁ, Eliška (203 Czech Republic, belonging to the institution), Radka OPATŘILOVÁ (203 Czech Republic, belonging to the institution), Peter SCHEER (203 Czech Republic, belonging to the institution), Jana HLOŽKOVÁ (203 Czech Republic, belonging to the institution), Sandra THALEROVÁ (203 Czech Republic), Ahmet Davut AKSU (792 Turkey, belonging to the institution) and Robert MIKULÍK (203 Czech Republic)
Edition
51st Conference Synthesis and Analysis of Drugs, Bratislava, September 7 & 8, 2023, 2023
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30104 Pharmacology and pharmacy
Country of publisher
Slovakia
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
RIV identification code
RIV/00216224:14160/23:00134678
Organization unit
Faculty of Pharmacy
Keywords (in Czech)
tromboembolie; skiaskopie; ischemická cévní mozková příhoda; altepláza
Keywords in English
thromboembolism; micro-fluoroscopy; ischemic stroke; limb ischemia; alteplase
Změněno: 29/2/2024 09:04, Mgr. Daniela Černá
Abstract
V originále
This innovative experimental work focuses on the development of targeted thrombolytics combinations for the diagnosis and therapy of cerebral infarction, their preparation and testing in a rat animal model. The effect of the addition of plasminogen to the standard recombinant alteplase in the treatment of cerebral infarction was tested. A rat model of systemic embolism was used for this purpose. The design of the model is set to simulate as much as possible the course of thrombolysis in the human organism and the implementation of preclinical research into clinical practice is realistic.
Links
| NU21-08-00510, research and development project |
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| NU23-08-00499, research and development project |
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