The prognostic value of CZT SPECT stress myocardial blood flow
(MBF) quantification—opportunity for stress-first/stress-only
protocol

J 2024

The prognostic value of CZT SPECT stress myocardial blood flow (MBF) quantification—opportunity for stress-first/stress-only protocol

KAMÍNEK, Milan, Martin HAVEL, Vladimír KINCL, Lenka HENZLOVA, Lenka HUDSON et. al.

Basic information

Original name

The prognostic value of CZT SPECT stress myocardial blood flow (MBF) quantification—opportunity for stress-first/stress-only protocol

Authors

KAMÍNEK, Milan (203 Czech Republic, belonging to the institution), Martin HAVEL (203 Czech Republic, guarantor), Vladimír KINCL (203 Czech Republic, belonging to the institution), Lenka HENZLOVA (203 Czech Republic) and Lenka HUDSON (203 Czech Republic)

Edition

European Journal of Nuclear Medicine and Molecular Imaging, NEW YORK, SPRINGER, 2024, 1619-7070

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 9.100 in 2022

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s00259-023-06531-7

UT WoS

001108438800001

Keywords in English

myocardial blood flow

Abstract

V originále

We read with great interest the recent article by Zhang et al. regarding the prognostic value of CZT SPECT myocardial blood flow (MBF) quantification. They studied a population of 118 patients with ischemia and no obstructive coronary artery disease (INOCA), all of whom underwent dynamic CZT SPECT imaging on a D-SPECT camera. During a median follow-up of 15 months, 19 major adverse cardiovascular events (MACEs) occurred. Both stress MBF and coronary flow reserve (CFR) were significantly lower in the MACE group. Compared with CFR, stress MBF provided a better prognostic model and remained a robust predictor of MACEs. Several studies previously confirmed feasibility, reproducibility, and good agreement in the calculation of MBF between CZT SPECT and PET-CT. Stress and rest MBF values obtained by CZT-SPECT are different than those measured by PET imaging and are usually higher, especially in the case of no attenuation correction (NAC) data. There can also be an influence of a flow model used for quantification of MBF on CZT SPECT. In the discussion, Zhang et al. mentioned a matter up for debate concerning which parameter (stress MBF or CFR) is better [1]. Results of their study suggest that stress MBF is superior to CFR. However, both stress MBF and CFR can be considered, at least if the values are assessed by means of CZT SPECT.

Citovat

KAMÍNEK, Milan, Martin HAVEL, Vladimír KINCL, Lenka HENZLOVA and Lenka HUDSON. The prognostic value of CZT SPECT stress myocardial blood flow (MBF) quantification—opportunity for stress-first/stress-only protocol. European Journal of Nuclear Medicine and Molecular Imaging. NEW YORK: SPRINGER, 2024, vol. 51, No 2, p. 344-345. ISSN 1619-7070. Available from: https://dx.doi.org/10.1007/s00259-023-06531-7.

@article{2344000,
   author = {Kamínek, Milan and Havel, Martin and Kincl, Vladimír and Henzlova, Lenka and Hudson, Lenka},
   article_location = {NEW YORK},
   article_number = {2},
   doi = {http://dx.doi.org/10.1007/s00259-023-06531-7},
   keywords = {myocardial blood flow},
   language = {eng},
   issn = {1619-7070},
   journal = {European Journal of Nuclear Medicine and Molecular Imaging},
   title = {The prognostic value of CZT SPECT stress myocardial blood flow (MBF) quantification—opportunity for stress-first/stress-only protocol},
   url = {https://link.springer.com/article/10.1007/s00259-023-06531-7},
   volume = {51},
   year = {2024}
}

TY  - JOUR
ID  - 2344000
AU  - Kamínek, Milan - Havel, Martin - Kincl, Vladimír - Henzlova, Lenka - Hudson, Lenka
PY  - 2024
TI  - The prognostic value of CZT SPECT stress myocardial blood flow (MBF) quantification—opportunity for stress-first/stress-only protocol
JF  - European Journal of Nuclear Medicine and Molecular Imaging
VL  - 51
IS  - 2
SP  - 344-345
EP  - 344-345
PB  - SPRINGER
SN  - 16197070
KW  - myocardial blood flow
UR  - https://link.springer.com/article/10.1007/s00259-023-06531-7
N2  - We read with great interest the recent article by Zhang et al. regarding the prognostic value of CZT SPECT myocardial blood flow (MBF) quantification. They studied a population of 118 patients with ischemia and no obstructive coronary artery disease (INOCA), all of whom underwent dynamic CZT SPECT imaging on a D-SPECT camera. During a median follow-up of 15 months, 19 major adverse cardiovascular events (MACEs) occurred. Both stress MBF and coronary flow reserve (CFR) were significantly lower in the MACE group. Compared with CFR, stress MBF provided a better prognostic model and remained a robust predictor of MACEs. Several studies previously confirmed feasibility, reproducibility, and good agreement in the calculation of MBF between CZT SPECT and PET-CT. Stress and rest MBF values obtained by CZT-SPECT are different than those measured by PET imaging and are usually higher, especially in the case of no attenuation correction (NAC) data. There can also be an influence of a flow model used for quantification of MBF on CZT SPECT. In the discussion, Zhang et al. mentioned a matter up for debate concerning which parameter (stress MBF or CFR) is better [1]. Results of their study suggest that stress MBF is superior to CFR. However, both stress MBF and CFR can be considered, at least if the values are assessed by means of CZT SPECT.
ER  -

KAMÍNEK, Milan, Martin HAVEL, Vladimír KINCL, Lenka HENZLOVA and Lenka HUDSON. The prognostic value of CZT SPECT stress myocardial blood flow (MBF) quantification—opportunity for stress-first/stress-only protocol. \textit{European Journal of Nuclear Medicine and Molecular Imaging}. NEW YORK: SPRINGER, 2024, vol.~51, No~2, p.~344-345. ISSN~1619-7070. Available from: https://dx.doi.org/10.1007/s00259-023-06531-7.

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