Detailed Information on Publication Record
2023
Trunk muscle dysfunction in patients with myotonic dystrophy type 2 and its contribution to chronic low back pain
VLAŽNÁ, Daniela, Peter KRKOŠKA, Michaela SLÁDEČKOVÁ, Olesja PARMOVÁ, Tamara BARUSOVÁ et. al.Basic information
Original name
Trunk muscle dysfunction in patients with myotonic dystrophy type 2 and its contribution to chronic low back pain
Authors
VLAŽNÁ, Daniela (703 Slovakia, belonging to the institution), Peter KRKOŠKA (703 Slovakia, belonging to the institution), Michaela SLÁDEČKOVÁ (203 Czech Republic, belonging to the institution), Olesja PARMOVÁ (203 Czech Republic), Tamara BARUSOVÁ (703 Slovakia), Karolína HRABCOVÁ (203 Czech Republic), Stanislav VOHÁŇKA (203 Czech Republic, belonging to the institution), Kateřina MATULOVÁ (203 Czech Republic, belonging to the institution) and Blanka ADAMOVÁ (203 Czech Republic, guarantor, belonging to the institution)
Edition
Frontiers in Neurology, Lausanne, Frontiers, 2023, 1664-2295
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30210 Clinical neurology
Country of publisher
Switzerland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 3.400 in 2022
RIV identification code
RIV/00216224:14110/23:00132387
Organization unit
Faculty of Medicine
UT WoS
001099114100001
Keywords in English
myotonic dystrophy type 2 (MD2); function tests; neuromuscular diseases (NMD); low back pain; paraspinal muscles; muscle strength; muscular endurance; respiratory muscles
Tags
International impact, Reviewed
Změněno: 5/4/2024 08:57, Mgr. Tereza Miškechová
Abstract
V originále
IntroductionMyotonic dystrophy type 2 (MD2) presents with a varied manifestation. Even though the myopathy in these patients is more widespread, axial musculature involvement is one of the most prominent conditions. MD2 patients also often report chronic low back pain (CLBP). The purpose of this study was to evaluate trunk muscle function, including respiratory muscles, in patients with MD2 and to compare it with healthy controls, to determine the occurrence of CLBP in patients with MD2, and to assess whether trunk muscle dysfunction increases the risk of CLBP in these patients.MethodsWe enrolled 40 MD2 patients (age range 23 to 76 years, 26 women). A comprehensive battery of tests was used to evaluate trunk muscle function. The tests consisted of quantitative muscle strength testing of low back extensor muscles and respiratory muscles and the assessment of trunk muscle endurance. A neurological evaluation contained procedures assessing the distribution of muscle weakness, myotonia, and pain, and used questionnaires focused on these items and on disability, depression, and physical activity.ResultsThe results of this study suggest that patients with MD2 show significant dysfunction of the trunk muscles, including the respiratory muscles, expressed by decreased muscle strength and endurance. The prevalence of CLBP in patients with MD2 was 52.5%. Based on our analysis, the only independent significant risk factor for CLBP in these patients was maximal isometric lower back extensor strength in a prone position <= 15.8 kg (OR = 37.3). Other possible risk factors were severity of myotonia and reduced physical activity.ConclusionOutcomes of this study highlighted the presence of axial muscle dysfunction, respiratory muscle weakness, and frequent occurrence of CLBP together with its risk factors in patients with MD2. We believe that the findings of this study may help in management and prevention programs for patients with MD2.
Links
EF19_073/0016943, research and development project |
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MUNI/A/1144/2021, interní kód MU |
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MUNI/A/1186/2022, interní kód MU |
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MUNI/IGA/1162/2021, interní kód MU |
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