DUBOVÝ, Petr, Ivana SVÍŽENSKÁ, Radim JANČÁLEK and Ilona KLUSÁKOVÁ. Immunohistochemical localization of some extracellular molecules and their integrin receptors in the rat Pacinian corpuscles. General Physiology and Biophysics. Bratislava: Veda, 1999, vol. 18, No 1, p. 66-68. ISSN 0231-5882.
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Basic information
Original name Immunohistochemical localization of some extracellular molecules and their integrin receptors in the rat Pacinian corpuscles
Name in Czech Imunohistochemická lokalizace ECM molekul a jejich integrinových řetězců v Paviniho tělísku
Authors DUBOVÝ, Petr (203 Czech Republic, guarantor), Ivana SVÍŽENSKÁ (203 Czech Republic), Radim JANČÁLEK (203 Czech Republic) and Ilona KLUSÁKOVÁ (203 Czech Republic).
Edition General Physiology and Biophysics, Bratislava, Veda, 1999, 0231-5882.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.400
RIV identification code RIV/00216224:14110/99:00001801
Organization unit Faculty of Medicine
Keywords in English Integrin receptors; Laminin-1 and 3; Specialized Schwann cells
Tags Integrin receptors, Laminin-1 and 3, Specialized Schwann cells
Tags International impact, Reviewed
Changed by Changed by: prof. RNDr. Petr Dubový, CSc., učo 698. Changed: 17/6/2009 12:20.
Abstract
The present results suggest that laminin-1 and 3 are localized in the specialized Schwann cells of Pacinian corpuscles, in spite of incomplete deposition of the basal lamina on the surface of their cytoplasmic processes. In addition, laminin-3 is concentrated and probably function as a stop protein not only in the neuromuscular junction, but also in the specialized Schwann cells enveloping the dendritic zone of the afferent axon. No significant changes of immunostaining for both laminins and their integrin receptors following denervation of Pacinian corpuscles indicate that their synthesis is independent to afferent axon as a prerequisite for successful reinnervation.
Abstract (in Czech)
Přítomnost lamininu-1 a -3 a jejich integrinových řetězců byly imunohistochemicky studovány v Paciniho tělískách potkana.
Links
GA309/97/0107, research and development projectName: Exprese integrinů při diferenciaci Schwannových buněk a odvozených struktur v periferní nervové soustavě laboratorního potkana
Investor: Czech Science Foundation, Expression of integrins during differentiation of Schwann cells and derivative structures of the peripheral nervous system of the rat
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