J 1999

Immunohistochemical localization of some extracellular molecules and their integrin receptors in the rat Pacinian corpuscles

DUBOVÝ, Petr, Ivana SVÍŽENSKÁ, Radim JANČÁLEK and Ilona KLUSÁKOVÁ

Basic information

Original name

Immunohistochemical localization of some extracellular molecules and their integrin receptors in the rat Pacinian corpuscles

Name in Czech

Imunohistochemická lokalizace ECM molekul a jejich integrinových řetězců v Paviniho tělísku

Authors

DUBOVÝ, Petr (203 Czech Republic, guarantor), Ivana SVÍŽENSKÁ (203 Czech Republic), Radim JANČÁLEK (203 Czech Republic) and Ilona KLUSÁKOVÁ (203 Czech Republic)

Edition

General Physiology and Biophysics, Bratislava, Veda, 1999, 0231-5882

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Slovakia

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.400

RIV identification code

RIV/00216224:14110/99:00001801

Organization unit

Faculty of Medicine

Keywords in English

Integrin receptors; Laminin-1 and 3; Specialized Schwann cells

Tags

Tags

International impact, Reviewed
Změněno: 17/6/2009 12:20, prof. RNDr. Petr Dubový, CSc.

Abstract

ORIG CZ

V originále

The present results suggest that laminin-1 and 3 are localized in the specialized Schwann cells of Pacinian corpuscles, in spite of incomplete deposition of the basal lamina on the surface of their cytoplasmic processes. In addition, laminin-3 is concentrated and probably function as a stop protein not only in the neuromuscular junction, but also in the specialized Schwann cells enveloping the dendritic zone of the afferent axon. No significant changes of immunostaining for both laminins and their integrin receptors following denervation of Pacinian corpuscles indicate that their synthesis is independent to afferent axon as a prerequisite for successful reinnervation.

In Czech

Přítomnost lamininu-1 a -3 a jejich integrinových řetězců byly imunohistochemicky studovány v Paciniho tělískách potkana.

Links

GA309/97/0107, research and development project
Name: Exprese integrinů při diferenciaci Schwannových buněk a odvozených struktur v periferní nervové soustavě laboratorního potkana
Investor: Czech Science Foundation, Expression of integrins during differentiation of Schwann cells and derivative structures of the peripheral nervous system of the rat