P 2023

Substituted aminothiazoles as inhibitors of nucleases

PARUCH, Kamil, Benoit Jean-Pierre CARBAIN, Štěpán HAVEL, Jiří DAMBORSKÝ, Jan BREZOVSKÝ et. al.

Basic information

Original name

Substituted aminothiazoles as inhibitors of nucleases

Name (in English)

Substituted aminothiazoles as inhibitors of nucleases

Authors

PARUCH, Kamil (203 Czech Republic, belonging to the institution), Benoit Jean-Pierre CARBAIN (250 France, belonging to the institution), Štěpán HAVEL (203 Czech Republic, belonging to the institution), Jiří DAMBORSKÝ (203 Czech Republic, belonging to the institution), Jan BREZOVSKÝ (203 Czech Republic, belonging to the institution), Lukáš DANIEL (203 Czech Republic, belonging to the institution), Alexandra SISÁKOVÁ (703 Slovakia, belonging to the institution), Fedor NIKULENKOV (203 Czech Republic, belonging to the institution) and Lumír KREJČÍ (203 Czech Republic, belonging to the institution)

Edition

Number: IL277866, Publisher: Israel Patent Office, Place of publication: Jerusalem, Owner's name: Masarykova univerzita, 2023

Other information

Language

Yiddish

Type of outcome

Patent

Field of Study

30107 Medicinal chemistry

Country of publisher

Israel

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/23:00132705

Organization unit

Faculty of Science

Keywords in English

DNA; propanamide; nuclease

Tags

Tags

International impact
Změněno: 6/8/2024 10:37, Mgr. Marie Šípková, DiS.

Abstract

V originále

Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

In English

Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.