KŘIVÁNEK, Jan, Kaj FRIED and Igor ADAMEYKO. On Dental Cell Types and Cell Populations, Also in Light of Evolution. Online. In Odontodes : the developmental and evolutionary building blocks of dentitions. Boca Raton: CRC Press, 2023, p. 1-48. 1st Edition. ISBN 978-1-003-43965-3. Available from: https://dx.doi.org/10.1201/9781003439653.
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Basic information
Original name On Dental Cell Types and Cell Populations, Also in Light of Evolution
Authors KŘIVÁNEK, Jan (203 Czech Republic, belonging to the institution), Kaj FRIED and Igor ADAMEYKO (752 Sweden).
Edition Boca Raton, Odontodes : the developmental and evolutionary building blocks of dentitions, p. 1-48, 48 pp. 1st Edition, 2023.
Publisher CRC Press
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 10605 Developmental biology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form electronic version available online
WWW URL
RIV identification code RIV/00216224:14110/23:00132720
Organization unit Faculty of Medicine
ISBN 978-1-003-43965-3
Doi http://dx.doi.org/10.1201/9781003439653
Keywords in English Dental Cell Types; Cell Populations
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 21/3/2024 10:16.
Abstract
Odontodes are diverse and complex structures built by a plethora of cell types arising from different embryonic origins and located inside and outside of the mouth cavity. Understanding a spectrum of cell types building teeth and other odontodes, as well as their development, molecular programs, and, importantly, their evolution, is a key for understanding the diversity and progression of vertebrate animals in general, as protection, mastication, feeding tactics, and fending are key for adaptability and survival of the fittest. Here, we focus on teeth, their diversity, and cellular composition. Therefore, this chapter provides an overview of cell types, primarily building teeth and, especially, generating dental biomineralized tissues of different composition and evolutionary history. Furthermore, we talk about the recent progress in tracking the development and identity of dental cell types, which was fueled by a recent combination of single-cell transcriptomics and lineage-tracing methodologies. The developmental aspects are discussed for every major dental cell type and cell lineage, focusing in depth on epithelial and mesenchymal compartments. Finally, we introduce evolving molecular programs and cellular properties, equipping cells with functional features and directing their evolutionary diversification in a variety of teeth.
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