Biaxial stretch can overcome discrepancy between global and
local orientations of wavy collagen fibres

J 2023

Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres

TURCANOVA, Michaela, Jiri FISCHER, Markéta HERMANOVÁ, Zdeněk BEDNAŘÍK, Pavel SKACEL et. al.

Basic information

Original name

Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres

Authors

TURCANOVA, Michaela (203 Czech Republic, guarantor), Jiri FISCHER (203 Czech Republic), Markéta HERMANOVÁ (203 Czech Republic, belonging to the institution), Zdeněk BEDNAŘÍK (203 Czech Republic, belonging to the institution), Pavel SKACEL (203 Czech Republic) and Jiri BURSA (203 Czech Republic)

Edition

JOURNAL OF BIOMECHANICS, OXFORD, ELSEVIER SCI LTD, 2023, 0021-9290

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

20302 Applied mechanics

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.400 in 2022

RIV identification code

RIV/00216224:14110/23:00134348

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.jbiomech.2023.111868

UT WoS

001115580000001

Keywords in English

Arterial wall; Collagen; Fibre direction; Fibre waviness; Concentration parameter

Abstract

V originále

Most frequently used structure-based constitutive models of arterial wall apply assumptions on two symmetric helical (and dispersed) fibre families which, however, are not well supported with histological findings where two collagen fibre families are seldom found. Moreover, bimodal distributions of fibre directions may originate also from their waviness combined with ignoring differences between local and global fibre orientations. In contrast, if the model parameters are identified without histological information on collagen fibre directions, the resulting mean angles of both fibre families are close to +/- 45 degrees, which contradicts nearly all histologic findings. The presented study exploited automated polarized light microscopy for detection of collagen fibre directions in porcine aorta under different biaxial extensions and approximated the resulting histograms with unimodal and bimodal von Mises distributions. Their comparison showed dominantly circumferential orientation of collagen fibres. Their concentration parameter for unimodal distributions increased with circumferential load, no matter if acting uniaxially or equibiaxially. For bimodal distributions, the angle between both dominant fibre directions (chosen as measure of fibre alignment) decreased similarly for both uniaxial and equibiaxial loads. These results indicate the existence of a single family of wavy circumferential collagen fibres in all layers of the aortic wall. Bimodal distributions of fibre directions presented sometimes in literature may come rather from waviness of circumferentially arranged fibres than from two symmetric families of helical fibres. To obtain a final evidence, the fibre orientation should be analysed together with their waviness.

Links

GA21-21935S, research and development project

Name: Výpočtové modelování pulzačního proudění v poddajných trubicích s aplikací na tandemovou stenózu karotidy

Investor: Czech Science Foundation

Citovat

TURCANOVA, Michaela, Jiri FISCHER, Markéta HERMANOVÁ, Zdeněk BEDNAŘÍK, Pavel SKACEL and Jiri BURSA. Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres. JOURNAL OF BIOMECHANICS. OXFORD: ELSEVIER SCI LTD, 2023, vol. 161, December 2023, p. 1-8. ISSN 0021-9290. Available from: https://dx.doi.org/10.1016/j.jbiomech.2023.111868.

@article{2355281,
   author = {Turcanova, Michaela and Fischer, Jiri and Hermanová, Markéta and Bednařík, Zdeněk and Skacel, Pavel and Bursa, Jiri},
   article_location = {OXFORD},
   article_number = {December 2023},
   doi = {http://dx.doi.org/10.1016/j.jbiomech.2023.111868},
   keywords = {Arterial wall; Collagen; Fibre direction; Fibre waviness; Concentration parameter},
   language = {eng},
   issn = {0021-9290},
   journal = {JOURNAL OF BIOMECHANICS},
   title = {Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres},
   url = {https://www.sciencedirect.com/science/article/pii/S0021929023004396?via%3Dihub},
   volume = {161},
   year = {2023}
}

TY  - JOUR
ID  - 2355281
AU  - Turcanova, Michaela - Fischer, Jiri - Hermanová, Markéta - Bednařík, Zdeněk - Skacel, Pavel - Bursa, Jiri
PY  - 2023
TI  - Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres
JF  - JOURNAL OF BIOMECHANICS
VL  - 161
IS  - December 2023
SP  - 1-8
EP  - 1-8
PB  - ELSEVIER SCI LTD
SN  - 00219290
KW  - Arterial wall
KW  - Collagen
KW  - Fibre direction
KW  - Fibre waviness
KW  - Concentration parameter
UR  - https://www.sciencedirect.com/science/article/pii/S0021929023004396?via%3Dihub
N2  - Most frequently used structure-based constitutive models of arterial wall apply assumptions on two symmetric helical (and dispersed) fibre families which, however, are not well supported with histological findings where two collagen fibre families are seldom found. Moreover, bimodal distributions of fibre directions may originate also from their waviness combined with ignoring differences between local and global fibre orientations. In contrast, if the model parameters are identified without histological information on collagen fibre directions, the resulting mean angles of both fibre families are close to +/- 45 degrees, which contradicts nearly all histologic findings. The presented study exploited automated polarized light microscopy for detection of collagen fibre directions in porcine aorta under different biaxial extensions and approximated the resulting histograms with unimodal and bimodal von Mises distributions. Their comparison showed dominantly circumferential orientation of collagen fibres. Their concentration parameter for unimodal distributions increased with circumferential load, no matter if acting uniaxially or equibiaxially. For bimodal distributions, the angle between both dominant fibre directions (chosen as measure of fibre alignment) decreased similarly for both uniaxial and equibiaxial loads. These results indicate the existence of a single family of wavy circumferential collagen fibres in all layers of the aortic wall. Bimodal distributions of fibre directions presented sometimes in literature may come rather from waviness of circumferentially arranged fibres than from two symmetric families of helical fibres. To obtain a final evidence, the fibre orientation should be analysed together with their waviness.
ER  -

TURCANOVA, Michaela, Jiri FISCHER, Markéta HERMANOVÁ, Zdeněk BEDNAŘÍK, Pavel SKACEL and Jiri BURSA. Biaxial stretch can overcome discrepancy between global and local orientations of wavy collagen fibres. \textit{JOURNAL OF BIOMECHANICS}. OXFORD: ELSEVIER SCI LTD, 2023, vol.~161, December 2023, p.~1-8. ISSN~0021-9290. Available from: https://dx.doi.org/10.1016/j.jbiomech.2023.111868.

Detailed Information on Publication Record