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@proceedings{2357187, author = {Škovranová, Gabriela and Molčanová, Lenka and Klančnik, Anja and Jug, Blaž and SmoleandMožina, Sonja and Sychrová, Alice}, booktitle = {PSE Young Scientists’ Meeting 28th – 30th June 2023, Paris, France}, keywords = {antibacterial activity; Paulownia tomentosa; quorum-sensing inhibition; Staphylococcus aureus; wound healing}, language = {eng}, title = {Paulownia tomentosa fruit extracts activity in eradication of Staphylococcus aureus}, year = {2023} }
TY - CONF ID - 2357187 AU - Škovranová, Gabriela - Molčanová, Lenka - Klančnik, Anja - Jug, Blaž - Smole-Možina, Sonja - Sychrová, Alice PY - 2023 TI - Paulownia tomentosa fruit extracts activity in eradication of Staphylococcus aureus KW - antibacterial activity KW - Paulownia tomentosa KW - quorum-sensing inhibition KW - Staphylococcus aureus KW - wound healing N2 - Staphylococcus aureus has a broad virulence capacity and biofilm formation limits the control of wound infections. Paulownia tomentosa Steud. (Paulowniaceae) is a rich source of geranylated phenolics responsible for various bioactivities. Ethanolic extract, chloroform fraction, and three flavonoids showed significant antimicrobial activity. In combination with fusidic acid and mupirocin, synergistic potential was observed. Membrane disruption is partly responsible for the antimicrobial activity of geranylated flavonoids. Selected plant formulations reduced the adhesion of bacteria to the abiotic surface, and also the inhibition of intercellular communication and quorum-sensing was described. ER -
ŠKOVRANOVÁ, Gabriela, Lenka MOLČANOVÁ, Anja KLANČNIK, Blaž JUG, Sonja SMOLE-MOŽINA and Alice SYCHROVÁ. Paulownia tomentosa fruit extracts activity in eradication of Staphylococcus aureus. In \textit{PSE Young Scientists’ Meeting 28th – 30th June 2023, Paris, France}. 2023.
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