a 2023

CLLue: Searching for connections among clinical, biological, and molecular features in the dataset of leukemia patients.

REIGL, Tomáš, Veronika NAVRKALOVÁ, Jakub Paweł PORC, Karol PÁL, Kamila STRÁNSKÁ et. al.

Basic information

Original name

CLLue: Searching for connections among clinical, biological, and molecular features in the dataset of leukemia patients.

Authors

REIGL, Tomáš (203 Czech Republic, belonging to the institution), Veronika NAVRKALOVÁ (203 Czech Republic, belonging to the institution), Jakub Paweł PORC (616 Poland, belonging to the institution), Karol PÁL (703 Slovakia, belonging to the institution), Kamila STRÁNSKÁ (203 Czech Republic, belonging to the institution), Šárka POSPÍŠILOVÁ (203 Czech Republic, guarantor) and Karla PLEVOVÁ (203 Czech Republic, belonging to the institution)

Edition

EMBL Conference Cancer Genomics 2023, Heidelberg, Německo, 2023

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30204 Oncology

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14740/23:00132956

Organization unit

Central European Institute of Technology

Keywords in English

chronic lymphocytic leukemia; visualizations in CLLue;

Tags

Tags

International impact, Reviewed
Změněno: 27/3/2024 11:45, Mgr. Eva Dubská

Abstract

V originále

Today’s analytic techniques produce extensive molecular biological and genetic information for every tumor sample. Understanding the significance of each feature and its connections with a patient's clinical history is one of the greatest challenges. Advanced computational approaches can provide such information, leading to the discovery of novel attributes critical for diagnosis and potentially new classifiers for categorizing patients into distinct groups. We investigated such attributes in a local dataset of patients with chronic lymphocytic leukemia (CLL).

Links

LM2018140, research and development project
Name: e-Infrastruktura CZ (Acronym: e-INFRA CZ)
Investor: Ministry of Education, Youth and Sports of the CR
LX22NPO5102, research and development project
Name: Národní ústav pro výzkum rakoviny (Acronym: NÚVR)
Investor: Ministry of Education, Youth and Sports of the CR, National institute for cancer research, 5.1 EXCELES
NU21-08-00237, research and development project
Name: Pokročilé sekvenační metody pro analýzu strukturních přestaveb nádorového genomu
Investor: Ministry of Health of the CR, Advanced sequencing methods for deciphering structural variants in cancer genome, Subprogram 1 - standard
NU22-08-00227, research and development project
Name: Pokročilé molekulární analýzy pro komplexní diagnostiku a monitorování pacientů s difúzním velkobuněčným B-lymfomem: využití profilování genové exprese, tekutých biopsií a sekvenování třetí generace
Investor: Ministry of Health of the CR, Advanced molecular testing for aggregate diagnosis and management of DLBCL patients: engagement of gene expression profiling, liquid biopsy and long-read sequencing, Subprogram 1 - standard