| NIKOLI, Marek, Vojtech VIKTORIN, Peter ZACH, Filip TYLS, Daniela DUDYSOVA, Karolina JANKU, Jana KOPIVOVA, Martin KUCHAR, Martin BRUNOVSKY, Jiri HORACEK and Tomas PALENICEK. Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis. European Neuropsychopharmacology. Amsterdam (The Netherlands): Elsevier, 2023, vol. 74, na, p. 78-88. ISSN 0924-977X. Available from: https://dx.doi.org/10.1016/j.euroneuro.2023.04.019. |
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@article{2359927,
author = {Nikoli, Marek and Viktorin, Vojtech and Zach, Peter and Tyls, Filip and Dudysova, Daniela and Janku, Karolina and Kopivova, Jana and Kuchar, Martin and Brunovsky, Martin and Horacek, Jiri and Palenicek, Tomas},
article_location = {Amsterdam (The Netherlands)},
article_number = {na},
doi = {http://dx.doi.org/10.1016/j.euroneuro.2023.04.019},
keywords = {Psilocybin; Psychedelics; Healthy volunteers; Memory consolidation; Cognition},
language = {eng},
issn = {0924-977X},
journal = {European Neuropsychopharmacology},
title = {Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis},
url = {https://www.sciencedirect.com/science/article/pii/S0924977X23000937?viaDihub},
volume = {74},
year = {2023}
}
TY - JOUR
ID - 2359927
AU - Nikoli, Marek - Viktorin, Vojtech - Zach, Peter - Tyls, Filip - Dudysova, Daniela - Janku, Karolina - Kopivova, Jana - Kuchar, Martin - Brunovsky, Martin - Horacek, Jiri - Palenicek, Tomas
PY - 2023
TI - Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis
JF - European Neuropsychopharmacology
VL - 74
IS - na
SP - 78-88
EP - 78-88
PB - Elsevier
SN - 0924977X
KW - Psilocybin
KW - Psychedelics
KW - Healthy volunteers
KW - Memory consolidation
KW - Cognition
UR - https://www.sciencedirect.com/science/article/pii/S0924977X23000937?viaDihub
N2 - Psilocybin is investigated as a fast-acting antidepressant used in conjunction with psychother-apy. Intact cognitive functions, including memory, are one of the basic conditions of effective psychedelic-assisted therapy. While cognitive and memory processing is attenuated on various domains during psilocybin intoxication, the effect of psilocybin on the consolidation of memo-ries learned outside of acute intoxication is not known. Thus the main aim of the current study was to test the effects of psilocybin on (A) memory consolidation of previously learned material just after the psilocybin session and (B) on overnight memory consolidation the night just after the psilocybin session. 20 healthy volunteers (10 M/10F) were enrolled in a placebo-controlled, double-blind, cross-over design. Effects on declarative memory consolidation in condition (A) The Groton Maze Learning Task and Rey Auditory Verbal Learning Test were used, and for (B) the Pair Associative Learning Test was used. We did not find psilocybin to improve memory consoli-dation. At the same time, we did not find psilocybin to negatively affect memory consolidation in any of the tests used. This evidence adds to the safety profile for the use of psilocybin.& COPY; 2023 Elsevier B.V. and ECNP. All rights reserved.
ER -
NIKOLI, Marek, Vojtech VIKTORIN, Peter ZACH, Filip TYLS, Daniela DUDYSOVA, Karolina JANKU, Jana KOPIVOVA, Martin KUCHAR, Martin BRUNOVSKY, Jiri HORACEK and Tomas PALENICEK. Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis. \textit{European Neuropsychopharmacology}. Amsterdam (The Netherlands): Elsevier, 2023, vol.~74, na, p.~78-88. ISSN~0924-977X. Available from: https://dx.doi.org/10.1016/j.euroneuro.2023.04.019.
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