GIMUNOVÁ, Marta, Ana Carolina PALUDO, Martina BERNACIKOVÁ and Julie DOBROVOLNÁ. The effect of space travel on human reproductive health: a systematic review. NPJ MICROGRAVITY. UNITED STATES: NATURE PORTFOLIO, 2024, vol. 10, No 10, p. 1-9. ISSN 2373-8065. Available from: https://dx.doi.org/10.1038/s41526-024-00351-1.
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Basic information
Original name The effect of space travel on human reproductive health: a systematic review
Authors GIMUNOVÁ, Marta (203 Czech Republic, guarantor, belonging to the institution), Ana Carolina PALUDO (76 Brazil, belonging to the institution), Martina BERNACIKOVÁ (203 Czech Republic, belonging to the institution) and Julie DOBROVOLNÁ (203 Czech Republic, belonging to the institution).
Edition NPJ MICROGRAVITY, UNITED STATES, NATURE PORTFOLIO, 2024, 2373-8065.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30300 3.3 Health sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW odkaz na full text
Impact factor Impact factor: 5.100 in 2022
Organization unit Faculty of Sports Studies
Doi http://dx.doi.org/10.1038/s41526-024-00351-1
UT WoS 001144704200001
Keywords in English space travel; reproductive health; astronauts
Tags International impact, Reviewed
Changed by Changed by: Mgr. Marta Gimunová, Ph.D., učo 358071. Changed: 5/2/2024 15:57.
Abstract
With increasing possibilities of multi-year missions in deep space, colonizing other planets, and space tourism, it is important to investigate the effects of space travel on human reproduction. This study aimed to systematically review and summarize the results of available literature on space travel, microgravity, and space radiation, or Earth-based spaceflight analogues impact on female and male reproductive functions in humans. This systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and Space Biomedicine Systematic Review methods. The search was performed using three databases: PubMed, Web of Science, and Medline Complete. During the database search, 364 studies were identified. After the study selection process, 16 studies were included in the review. Five studies included female participants, and the findings show an increased risk of thromboembolism in combined oral contraceptive users, decreased decidualization, functional insufficiency of corpus luteum, and decreased progesterone and LH levels related to space travel or its simulation. Male participants were included in 13 studies. In males, reproductive health considerations focused on the decrease in testosterone and sex hormone-binding globulin levels, the ratio of male offspring, sperm motility, sperm vitality, and the increase in sperm DNA fragmentation related to space travel or its simulation. Results of this systematic review highlight the need to focus more on the astronaut’s reproductive health in future research, as only 16 studies were found during the literature search, and many more research questions related to reproductive health in astronauts still need to be answered.
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