Pretreatment Cancer-Related Cognitive Impairment in Hodgkin
Lymphoma Patients

J 2023

Pretreatment Cancer-Related Cognitive Impairment in Hodgkin Lymphoma Patients

JURICKOVA, Veronika, Dan FAYETTE, Juraj JONAS, Iveta FAJNEROVA, Tomas KOZAK et. al.

Basic information

Original name

Pretreatment Cancer-Related Cognitive Impairment in Hodgkin Lymphoma Patients

Authors

JURICKOVA, Veronika, Dan FAYETTE, Juraj JONAS, Iveta FAJNEROVA, Tomas KOZAK and Jiri HORACEK

Edition

Current Oncology, Toronto, Multimed INC. 2023, 1198-0052

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30230 Other clinical medicine subjects

Country of publisher

Canada

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

PSIKET

Impact factor

Impact factor: 2.600 in 2022

RIV identification code

RIV/00216224:90249/23:00133240

DOI

http://dx.doi.org/10.3390/curroncol30100652

UT WoS

001119525500001

Keywords (in Czech)

kognitivní poruchy související s rakovinou; Hodgkinův lymfom; neuropsychologie; afektivní úzkost; kvalita života

Keywords in English

cancer-related cognitive impairment; Hodgkin lymphoma; neuropsychology; affective distress; quality of life

Abstract

V originále

Background: Cancer-related cognitive impairment (CRCI) is one of the most serious side effects of cancer that negatively impacts the quality of life of cancer patients and survivors. There is evidence of CRCI in Hodgkin lymphoma patients (HL); however, there is a lack of studies examining the presence of cognitive deficits before starting any treatment in HL patients. Methods: Forty adult patients (N = 40) newly diagnosed with HL (with no previous cancer diagnoses) and 40 healthy controls (N = 40) matched for age, sex, education, and premorbid intellect completed the neuropsychological battery and subjective and objective measures of affective distress and quality of life. Results: The results showed impairment in three out of six cognitive domains: verbal memory and learning, speed of processing/psychomotor speed, and abstraction/executive functions in the HL patients before the initiation of any treatment. The speed of processing/psychomotor speed domain is negatively correlated with depression. Conclusion: Cognitive deterioration in verbal memory and learning and abstraction/executive functions domains in HL patients seems to occur before the initiation of treatment independently of anxiety, depression, or physical symptoms. This suggests that HL itself may cause cognitive deficits in these cognitive domains. However, the underlying causes of CRCI still remain unclear.

Links

90249, large research infrastructures

Name: CZECRIN IV

Citovat

JURICKOVA, Veronika, Dan FAYETTE, Juraj JONAS, Iveta FAJNEROVA, Tomas KOZAK and Jiri HORACEK. Pretreatment Cancer-Related Cognitive Impairment in Hodgkin Lymphoma Patients. Current Oncology. Toronto: Multimed INC., 2023, vol. 30, No 10, p. 9028-9038. ISSN 1198-0052. Available from: https://dx.doi.org/10.3390/curroncol30100652.

@article{2365839,
   author = {Jurickova, Veronika and Fayette, Dan and Jonas, Juraj and Fajnerova, Iveta and Kozak, Tomas and Horacek, Jiri},
   article_location = {Toronto},
   article_number = {10},
   doi = {http://dx.doi.org/10.3390/curroncol30100652},
   keywords = {cancer-related cognitive impairment; Hodgkin lymphoma; neuropsychology; affective distress; quality of life},
   language = {eng},
   issn = {1198-0052},
   journal = {Current Oncology},
   title = {Pretreatment Cancer-Related Cognitive Impairment in Hodgkin Lymphoma Patients},
   url = {https://www.mdpi.com/1718-7729/30/10/652},
   volume = {30},
   year = {2023}
}

TY  - JOUR
ID  - 2365839
AU  - Jurickova, Veronika - Fayette, Dan - Jonas, Juraj - Fajnerova, Iveta - Kozak, Tomas - Horacek, Jiri
PY  - 2023
TI  - Pretreatment Cancer-Related Cognitive Impairment in Hodgkin Lymphoma Patients
JF  - Current Oncology
VL  - 30
IS  - 10
SP  - 9028-9038
EP  - 9028-9038
PB  - Multimed INC.
SN  - 11980052
KW  - cancer-related cognitive impairment
KW  - Hodgkin lymphoma
KW  - neuropsychology
KW  - affective distress
KW  - quality of life
UR  - https://www.mdpi.com/1718-7729/30/10/652
N2  - Background: Cancer-related cognitive impairment (CRCI) is one of the most serious side effects of cancer that negatively impacts the quality of life of cancer patients and survivors. There is evidence of CRCI in Hodgkin lymphoma patients (HL); however, there is a lack of studies examining the presence of cognitive deficits before starting any treatment in HL patients. Methods: Forty adult patients (N = 40) newly diagnosed with HL (with no previous cancer diagnoses) and 40 healthy controls (N = 40) matched for age, sex, education, and premorbid intellect completed the neuropsychological battery and subjective and objective measures of affective distress and quality of life. Results: The results showed impairment in three out of six cognitive domains: verbal memory and learning, speed of processing/psychomotor speed, and abstraction/executive functions in the HL patients before the initiation of any treatment. The speed of processing/psychomotor speed domain is negatively correlated with depression. Conclusion: Cognitive deterioration in verbal memory and learning and abstraction/executive functions domains in HL patients seems to occur before the initiation of treatment independently of anxiety, depression, or physical symptoms. This suggests that HL itself may cause cognitive deficits in these cognitive domains. However, the underlying causes of CRCI still remain unclear.
ER  -

JURICKOVA, Veronika, Dan FAYETTE, Juraj JONAS, Iveta FAJNEROVA, Tomas KOZAK and Jiri HORACEK. Pretreatment Cancer-Related Cognitive Impairment in Hodgkin Lymphoma Patients. \textit{Current Oncology}. Toronto: Multimed INC., 2023, vol.~30, No~10, p.~9028-9038. ISSN~1198-0052. Available from: https://dx.doi.org/10.3390/curroncol30100652.

Detailed Information on Publication Record