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@article{2367121,
author = {Bytesnikova, Zuzana and Kolackova, Martina and Dobesova, Marketa and Svec, Pavel and Ridoskova, Andrea and Pekarkova, Jana and Přibyl, Jan and Capal, Petr and Huska, Dalibor and Adam, Vojtech and Richtera, Lukas},
article_location = {NETHERLANDS},
article_number = {July},
doi = {http://dx.doi.org/10.1016/j.impact.2023.100468},
keywords = {Graphene oxide; Reduction; Toxicity; Biocompatibility; Chlamydomonas; Microalgae},
language = {eng},
issn = {2452-0748},
journal = {NANOIMPACT},
title = {New insight into the biocompatibility/toxicity of graphene oxides and their reduced forms on Chlamydomonas reinhardtii},
url = {https://www.sciencedirect.com/science/article/pii/S2452074823000198?via%3Dihub},
volume = {31},
year = {2023}
}
TY - JOUR
ID - 2367121
AU - Bytesnikova, Zuzana - Kolackova, Martina - Dobesova, Marketa - Svec, Pavel - Ridoskova, Andrea - Pekarkova, Jana - Přibyl, Jan - Capal, Petr - Huska, Dalibor - Adam, Vojtech - Richtera, Lukas
PY - 2023
TI - New insight into the biocompatibility/toxicity of graphene oxides and their reduced forms on Chlamydomonas reinhardtii
JF - NANOIMPACT
VL - 31
IS - July
SP - 1-12
EP - 1-12
PB - ELSEVIER
SN - 24520748
KW - Graphene oxide
KW - Reduction
KW - Toxicity
KW - Biocompatibility
KW - Chlamydomonas
KW - Microalgae
UR - https://www.sciencedirect.com/science/article/pii/S2452074823000198?via%3Dihub
N2 - Graphene oxides (GOs) and their reduced forms are often discussed both positively and negatively due to the of information about their chemistry and structure. This study utilized GOs with two sheet sizes that were further reduced by two reducing agents (sodium borohydride and hydrazine) to obtain two different degrees reduction. The synthesized nanomaterials were characterized using scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), elemental analysis (EA), Fourier transform infrared (FTIR) spectroscopy, and Raman spectroscopy (RA) to understand their chemistry and structure. second focus of our investigation included in vitro testing of the biocompatibility/toxicity of these materials model organism, the freshwater microalga Chlamydomonas reinhardtii. The effects were studied on the basis biological endpoints complemented by biomass investigation (FTIR spectroscopy, EA, and atomic absorption spectrometry (AAS)). The results showed that the biocompatibility/toxicity of GOs is dependent on chemistry and structure and that it is impossible to generalize the toxicity of graphene-based nanomaterials.
ER -
BYTESNIKOVA, Zuzana, Martina KOLACKOVA, Marketa DOBESOVA, Pavel SVEC, Andrea RIDOSKOVA, Jana PEKARKOVA, Jan PŘIBYL, Petr CAPAL, Dalibor HUSKA, Vojtech ADAM and Lukas RICHTERA. New insight into the biocompatibility/toxicity of graphene oxides and their reduced forms on Chlamydomonas reinhardtii. \textit{NANOIMPACT}. NETHERLANDS: ELSEVIER, 2023, vol.~31, July, p.~1-12. ISSN~2452-0748. Available from: https://dx.doi.org/10.1016/j.impact.2023.100468.
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