LISKOVA, Veronika, Barbora CHOVANCOVA, Petr BABULA, Ingeborg REZUCHOVA, Kristina Ploth PAVLOV, Miroslava MATUSKOVA and Oľga KRIŽANOVÁ. Cystathionine β-synthase affects organization of cytoskeleton and modulates carcinogenesis in colorectal carcinoma cells. Frontiers in Oncology. LAUSANNE: FRONTIERS MEDIA SA, 2023, vol. 13, July 2023, p. 1-13. ISSN 2234-943X. Available from: https://dx.doi.org/10.3389/fonc.2023.1178021.
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Basic information
Original name Cystathionine β-synthase affects organization of cytoskeleton and modulates carcinogenesis in colorectal carcinoma cells
Authors LISKOVA, Veronika, Barbora CHOVANCOVA, Petr BABULA (203 Czech Republic, belonging to the institution), Ingeborg REZUCHOVA, Kristina Ploth PAVLOV, Miroslava MATUSKOVA and Oľga KRIŽANOVÁ (703 Slovakia, guarantor, belonging to the institution).
Edition Frontiers in Oncology, LAUSANNE, FRONTIERS MEDIA SA, 2023, 2234-943X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30204 Oncology
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 4.700 in 2022
RIV identification code RIV/00216224:14110/23:00133290
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3389/fonc.2023.1178021
UT WoS 001034178500001
Keywords in English cystathionine beta-synthase; cytoskeleton; beta-tubulin; colorectal carcinoma cells; xenografts
Tags 14110515, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 29/1/2024 12:37.
Abstract
Background: Cystathionine beta-synthase (CBS), one of three enzymes that endogenously produce hydrogen sulfide, is extensively studied for its relevance in the cells of various tumors. In our previous work, we observed that the immunofluorescence pattern of CBS is very similar to that of tubulin and actin. Therefore, we focused on the potential interaction of CBS with cytoskeletal proteins beta-actin and beta-tubulin and the functional relevance of the potential interaction of these proteins in colorectal carcinoma cell lines.
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