Crystallization as a selection force at the polymerization of
nucleotides in a prebiotic context

J 2023

Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context

ŠPONER, Judit E., Jiří ŠPONER, Jakub VÝRAVSKÝ, Roman MATYÁŠEK, Aleš KOVAŘÍK et. al.

Basic information

Original name

Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context

Authors

ŠPONER, Judit E., Jiří ŠPONER, Jakub VÝRAVSKÝ (203 Czech Republic, belonging to the institution), Roman MATYÁŠEK, Aleš KOVAŘÍK, Wojciech DUDZIAK and Katarzyna ŚLEPOKURA

Edition

iScience, Cambridge, MA, USA, Cell Press, 2023, 2589-0042

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10505 Geology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.800 in 2022

RIV identification code

RIV/00216224:14310/23:00133323

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1016/j.isci.2023.107600

UT WoS

001067991400001

Keywords in English

Natural sciences; Biological sciences; Biochemistry

Abstract

V originále

Accumulation and selection of nucleotides is one of the most challenging problems surrounding the origin of the first RNA molecules on our planet. In the current work we propose that guanosine 3',5' cyclic mono phosphate could selectively crystallize upon evaporation of an acidic prebiotic pool containing various other nucleotides. The conditions of the evaporative crystallization are fully compatible with the subsequent acid catalyzed polymerization of this cyclic nucleotide reported in earlier studies and may be relevant in a broad range of possible prebiotic environments. Albeit cytidine 3',5' cyclic monophosphate has the ability to selectively accumulate under the same conditions, its crystal structure is not likely to support polymer formation.

Citovat

ŠPONER, Judit E., Jiří ŠPONER, Jakub VÝRAVSKÝ, Roman MATYÁŠEK, Aleš KOVAŘÍK, Wojciech DUDZIAK and Katarzyna ŚLEPOKURA. Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context. iScience. Cambridge, MA, USA: Cell Press, 2023, vol. 26, No 9, p. 1-15. ISSN 2589-0042. Available from: https://dx.doi.org/10.1016/j.isci.2023.107600.

@article{2367642,
   author = {Šponer, Judit E. and Šponer, Jiří and Výravský, Jakub and Matyášek, Roman and Kovařík, Aleš and Dudziak, Wojciech and Ślepokura, Katarzyna},
   article_location = {Cambridge, MA, USA},
   article_number = {9},
   doi = {http://dx.doi.org/10.1016/j.isci.2023.107600},
   keywords = {Natural sciences; Biological sciences; Biochemistry},
   language = {eng},
   issn = {2589-0042},
   journal = {iScience},
   title = {Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context},
   url = {https://www.sciencedirect.com/science/article/pii/S2589004223016772},
   volume = {26},
   year = {2023}
}

TY  - JOUR
ID  - 2367642
AU  - Šponer, Judit E. - Šponer, Jiří - Výravský, Jakub - Matyášek, Roman - Kovařík, Aleš - Dudziak, Wojciech - Ślepokura, Katarzyna
PY  - 2023
TI  - Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context
JF  - iScience
VL  - 26
IS  - 9
SP  - 1-15
EP  - 1-15
PB  - Cell Press
SN  - 25890042
KW  - Natural sciences
KW  - Biological sciences
KW  - Biochemistry
UR  - https://www.sciencedirect.com/science/article/pii/S2589004223016772
N2  - Accumulation and selection of nucleotides is one of the most challenging problems surrounding the origin of the first RNA molecules on our planet. In the current work we propose that guanosine 3',5' cyclic mono phosphate could selectively crystallize upon evaporation of an acidic prebiotic pool containing various other nucleotides. The conditions of the evaporative crystallization are fully compatible with the subsequent acid catalyzed polymerization of this cyclic nucleotide reported in earlier studies and may be relevant in a broad range of possible prebiotic environments. Albeit cytidine 3',5' cyclic monophosphate has the ability to selectively accumulate under the same conditions, its crystal structure is not likely to support polymer formation.
ER  -

ŠPONER, Judit E., Jiří ŠPONER, Jakub VÝRAVSKÝ, Roman MATYÁŠEK, Aleš KOVAŘÍK, Wojciech DUDZIAK and Katarzyna $\backslash$'SLEPOKURA. Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context. \textit{iScience}. Cambridge, MA, USA: Cell Press, 2023, vol.~26, No~9, p.~1-15. ISSN~2589-0042. Available from: https://dx.doi.org/10.1016/j.isci.2023.107600.

Detailed Information on Publication Record