Primary Breast Sarcoma: A Two-Centre Analysis and Review of
Literature

J 2023

Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature

ŽATECKÝ, Jan, Oldřich COUFAL, Pavel FABIAN, Miloš HOLÁNEK, Eva SEHNALKOVA et. al.

Basic information

Original name

Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature

Authors

ŽATECKÝ, Jan (203 Czech Republic, guarantor), Oldřich COUFAL (203 Czech Republic, belonging to the institution), Pavel FABIAN (203 Czech Republic), Miloš HOLÁNEK (203 Czech Republic, belonging to the institution), Eva SEHNALKOVA (203 Czech Republic) and Petr BURKOŇ (203 Czech Republic, belonging to the institution)

Edition

BREAST CARE, BASEL, KARGER, 2023, 1661-3791

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30204 Oncology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.100 in 2022

RIV identification code

RIV/00216224:14110/23:00133363

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1159/000530934

UT WoS

001010246100001

Keywords in English

Primary breast sarcoma; Prognostic factors; Two-centre analysis

Abstract

V originále

Introduction: Primary breast sarcoma is a very rare malignant type of breast tumours with an incidence of 0.1% of all primary breast malignancies. Methods: We present a retrospective analysis of the case series from two hospitals in the Czech Republic with a review of the diagnostic and treatment approach to primary breast sarcomas with an analysis of published prognostic factors. Results: Eleven patients were included in the study, 9 women and 2 men. Statistical evaluation revealed that tumour size (p = 0.1964), grade (p = 0.1667), margin distance (p = 0.5403), mitotic activity (p = 0.8577), or age (p = 0.7822) were not prognostic factors in our cohort. Conclusion: The analysis did not prove any of the factors, such as age, tumour size, grade, or mitotic activity, to be statistically significant prognostic factors. Based on the literature review, the most common published prognostic factors are tumour size, margin status, and grade, but the results are ambiguous.

Citovat

ŽATECKÝ, Jan, Oldřich COUFAL, Pavel FABIAN, Miloš HOLÁNEK, Eva SEHNALKOVA and Petr BURKOŇ. Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature. BREAST CARE. BASEL: KARGER, 2023, vol. 18, No 4, p. 262-269. ISSN 1661-3791. Available from: https://dx.doi.org/10.1159/000530934.

@article{2368497,
   author = {Žatecký, Jan and Coufal, Oldřich and Fabian, Pavel and Holánek, Miloš and Sehnalkova, Eva and Burkoň, Petr},
   article_location = {BASEL},
   article_number = {4},
   doi = {http://dx.doi.org/10.1159/000530934},
   keywords = {Primary breast sarcoma; Prognostic factors; Two-centre analysis},
   language = {eng},
   issn = {1661-3791},
   journal = {BREAST CARE},
   title = {Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature},
   url = {https://karger.com/brc/article/18/4/262/843569/Primary-Breast-Sarcoma-A-Two-Centre-Analysis-and},
   volume = {18},
   year = {2023}
}

TY  - JOUR
ID  - 2368497
AU  - Žatecký, Jan - Coufal, Oldřich - Fabian, Pavel - Holánek, Miloš - Sehnalkova, Eva - Burkoň, Petr
PY  - 2023
TI  - Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature
JF  - BREAST CARE
VL  - 18
IS  - 4
SP  - 262-269
EP  - 262-269
PB  - KARGER
SN  - 16613791
KW  - Primary breast sarcoma
KW  - Prognostic factors
KW  - Two-centre analysis
UR  - https://karger.com/brc/article/18/4/262/843569/Primary-Breast-Sarcoma-A-Two-Centre-Analysis-and
N2  - Introduction: Primary breast sarcoma is a very rare malignant type of breast tumours with an incidence of 0.1% of all primary breast malignancies. Methods: We present a retrospective analysis of the case series from two hospitals in the Czech Republic with a review of the diagnostic and treatment approach to primary breast sarcomas with an analysis of published prognostic factors. Results: Eleven patients were included in the study, 9 women and 2 men. Statistical evaluation revealed that tumour size (p = 0.1964), grade (p = 0.1667), margin distance (p = 0.5403), mitotic activity (p = 0.8577), or age (p = 0.7822) were not prognostic factors in our cohort. Conclusion: The analysis did not prove any of the factors, such as age, tumour size, grade, or mitotic activity, to be statistically significant prognostic factors. Based on the literature review, the most common published prognostic factors are tumour size, margin status, and grade, but the results are ambiguous.
ER  -

ŽATECKÝ, Jan, Oldřich COUFAL, Pavel FABIAN, Miloš HOLÁNEK, Eva SEHNALKOVA and Petr BURKOŇ. Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature. \textit{BREAST CARE}. BASEL: KARGER, 2023, vol.~18, No~4, p.~262-269. ISSN~1661-3791. Available from: https://dx.doi.org/10.1159/000530934.

Detailed Information on Publication Record