Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature

ŽATECKÝ, Jan, Oldřich COUFAL, Pavel FABIAN, Miloš HOLÁNEK, Eva SEHNALKOVA and Petr BURKOŇ. Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature. BREAST CARE. BASEL: KARGER, 2023, vol. 18, No 4, p. 262-269. ISSN 1661-3791. Available from: https://dx.doi.org/10.1159/000530934.

Basic information

• Original name: Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature
• Authors: ŽATECKÝ, Jan (203 Czech Republic, guarantor), Oldřich COUFAL (203 Czech Republic, belonging to the institution), Pavel FABIAN (203 Czech Republic), Miloš HOLÁNEK (203 Czech Republic, belonging to the institution), Eva SEHNALKOVA (203 Czech Republic) and Petr BURKOŇ (203 Czech Republic, belonging to the institution).
• Edition: BREAST CARE, BASEL, KARGER, 2023, 1661-3791.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30204 Oncology
• Country of publisher: Switzerland
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 2.100 in 2022
• RIV identification code: RIV/00216224:14110/23:00133363
• Organization unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1159/000530934
• UT WoS: 001010246100001
• Keywords in English: Primary breast sarcoma; Prognostic factors; Two-centre analysis
• Tags: 14110811, 14110813, rivok
• Tags: International impact, Reviewed

Abstract

Introduction: Primary breast sarcoma is a very rare malignant type of breast tumours with an incidence of 0.1% of all primary breast malignancies. Methods: We present a retrospective analysis of the case series from two hospitals in the Czech Republic with a review of the diagnostic and treatment approach to primary breast sarcomas with an analysis of published prognostic factors. Results: Eleven patients were included in the study, 9 women and 2 men. Statistical evaluation revealed that tumour size (p = 0.1964), grade (p = 0.1667), margin distance (p = 0.5403), mitotic activity (p = 0.8577), or age (p = 0.7822) were not prognostic factors in our cohort. Conclusion: The analysis did not prove any of the factors, such as age, tumour size, grade, or mitotic activity, to be statistically significant prognostic factors. Based on the literature review, the most common published prognostic factors are tumour size, margin status, and grade, but the results are ambiguous.