Benchmarking (i.e. comparison of quality and performance in a specifically designed way) of instruments and methods is a valuable tool to improve the experiments and services in the field of biophysics. It allows not only to compare the performance of individual laboratories/facilities but also helps to define the strong and weak points in particular measurement set-ups, offers an independent evaluation of individual instruments and therefore contributes to the retaining of the overall quality of science. Therefore, ARBRE has chosen benchmarking as one of its topics since the very beginning. Within the ARBRE-MOBIEU action, we have organized several runs of benchmarking focused on various methods, e.g. MST or ITC. The results were very beneficial and so we would like to continue in these activities further, covering more techniques as well as offering a platform for the design of more specific benchmark studies.