J 2023

Biopathology of childhood, adolescent and young adult non-Hodgkin lymphoma

LIM, Megan S, Michelle FOLEY, Lara MUSSOLIN, Reiner SIEBERT, Suzanne Dawn TURNER et. al.

Basic information

Original name

Biopathology of childhood, adolescent and young adult non-Hodgkin lymphoma

Authors

LIM, Megan S, Michelle FOLEY, Lara MUSSOLIN, Reiner SIEBERT and Suzanne Dawn TURNER (826 United Kingdom of Great Britain and Northern Ireland, guarantor, belonging to the institution)

Edition

BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, OXFORD, ELSEVIER SCI LTD, 2023, 1521-6926

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30205 Hematology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.100 in 2022

RIV identification code

RIV/00216224:14740/23:00133503

Organization unit

Central European Institute of Technology

UT WoS

000974139900001

Keywords in English

Pathobiology; Genetic; Childhood; Adolescent and young adult; Non -Hodgkin lymphoma

Tags

Tags

International impact, Reviewed
Změněno: 5/4/2024 10:49, Mgr. Eva Dubská

Abstract

V originále

Mature non-Hodgkin lymphomas (NHL) in the childhood, adolescent and young adult (CAYA) population are rare and exhibit unique clinical, immunophenotypic and genetic characteristics. Application of large-scale unbiased genomic and proteomic technologies such as gene expression profiling and next generation sequencing (NGS) have led to enhanced understanding of the genetic basis for many lymphomas in adults. However, studies to investigate the pathogenetic events in CAYA population are relatively sparse. Enhanced understanding of the pathobiologic mechanisms involved in non-Hodgkin lymphomas in this unique population will allow for improved recognition of these rare lymphomas. Elucidation of the pathobiologic differences between CAYA and adult lymphomas will also lead to the design of more rational and much needed, less toxic therapies for this population. In this review, we summarize recent insights gained from the proceedings of the recent 7th International CAYA NHL Symposium held in New York City, New York October 20-23, 2022.