PATERNOGA, Helge, Caillan CROWE-MCAULIFFE, Lars V BOCK, Timm O KOLLER, Martino MORICI, Bertrand BECKERT, Alexander G MYASNIKOV, Helmut GRUBMUELLER, Jiří NOVÁČEK and Daniel N WILSON. Structural conservation of antibiotic interaction with ribosomes. NATURE STRUCTURAL & MOLECULAR BIOLOGY. NEW YORK: NATURE PUBLISHING GROUP, 2023, vol. 30, No 9, p. 1380-1414. ISSN 1545-9993. Available from: https://dx.doi.org/10.1038/s41594-023-01047-y. |
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@article{2372337, author = {Paternoga, Helge and CroweandMcAuliffe, Caillan and Bock, Lars V and Koller, Timm O and Morici, Martino and Beckert, Bertrand and Myasnikov, Alexander G and Grubmueller, Helmut and Nováček, Jiří and Wilson, Daniel N}, article_location = {NEW YORK}, article_number = {9}, doi = {http://dx.doi.org/10.1038/s41594-023-01047-y}, keywords = {ribosome; antibiotics; CryoEM; antibiotic–ribosome interactions; RNA-targeting therapies}, language = {eng}, issn = {1545-9993}, journal = {NATURE STRUCTURAL & MOLECULAR BIOLOGY}, title = {Structural conservation of antibiotic interaction with ribosomes}, url = {https://www.nature.com/articles/s41594-023-01047-y}, volume = {30}, year = {2023} }
TY - JOUR ID - 2372337 AU - Paternoga, Helge - Crowe-McAuliffe, Caillan - Bock, Lars V - Koller, Timm O - Morici, Martino - Beckert, Bertrand - Myasnikov, Alexander G - Grubmueller, Helmut - Nováček, Jiří - Wilson, Daniel N PY - 2023 TI - Structural conservation of antibiotic interaction with ribosomes JF - NATURE STRUCTURAL & MOLECULAR BIOLOGY VL - 30 IS - 9 SP - 1380-1414 EP - 1380-1414 PB - NATURE PUBLISHING GROUP SN - 15459993 KW - ribosome KW - antibiotics KW - CryoEM KW - antibiotic–ribosome interactions KW - RNA-targeting therapies UR - https://www.nature.com/articles/s41594-023-01047-y N2 - Here the authors present the high-resolution structures of 17 antibiotics bound to Escherichia coli ribosomes, which may inform the development of new antibacterial agents. Their results unveil a conserved manner of antibiotic binding to the ribosome, including ordered water molecules. ER -
PATERNOGA, Helge, Caillan CROWE-MCAULIFFE, Lars V BOCK, Timm O KOLLER, Martino MORICI, Bertrand BECKERT, Alexander G MYASNIKOV, Helmut GRUBMUELLER, Jiří NOVÁČEK and Daniel N WILSON. Structural conservation of antibiotic interaction with ribosomes. \textit{NATURE STRUCTURAL \&{}amp; MOLECULAR BIOLOGY}. NEW YORK: NATURE PUBLISHING GROUP, 2023, vol.~30, No~9, p.~1380-1414. ISSN~1545-9993. Available from: https://dx.doi.org/10.1038/s41594-023-01047-y.
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