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@article{2375298,
author = {Raxwal, Vivek Kumar and Říha, Karel},
article_location = {London},
article_number = {1},
doi = {http://dx.doi.org/10.1042/BST20211231},
keywords = {alternative splicing; Arabidopsis thaliana; nonsense-mediated decay; post-transcriptional gene regulation},
language = {eng},
issn = {0300-5127},
journal = {Biochemical Society Transactions},
title = {The biological functions of nonsense-mediated mRNA decay in plants: RNA quality control and beyond},
url = {https://portlandpress.com/biochemsoctrans/article-abstract/51/1/31/232498/The-biological-functions-of-nonsense-mediated-mRNA?redirectedFrom=fulltext},
volume = {51},
year = {2023}
}
TY - JOUR
ID - 2375298
AU - Raxwal, Vivek Kumar - Říha, Karel
PY - 2023
TI - The biological functions of nonsense-mediated mRNA decay in plants: RNA quality control and beyond
JF - Biochemical Society Transactions
VL - 51
IS - 1
SP - 31-39
EP - 31-39
PB - Portland Press
SN - 03005127
KW - alternative splicing
KW - Arabidopsis thaliana
KW - nonsense-mediated decay
KW - post-transcriptional gene regulation
UR - https://portlandpress.com/biochemsoctrans/article-abstract/51/1/31/232498/The-biological-functions-of-nonsense-mediated-mRNA?redirectedFrom=fulltext
N2 - Nonsense-mediated mRNA decay (NMD) is an evolutionarily conserved quality control pathway that inhibits the expression of transcripts containing premature termination codon. Transcriptome and phenotypic studies across a range of organisms indicate roles of NMD beyond RNA quality control and imply its involvement in regulating gene expression in a wide range of physiological processes. Studies in moss Physcomitrella patens and Arabidopsis thaliana have shown that NMD is also important in plants where it contributes to the regulation of pathogen defence, hormonal signalling, circadian clock, reproduction and gene evolution. Here, we provide up to date overview of the biological functions of NMD in plants. In addition, we discuss several biological processes where NMD factors implement their function through NMD-independent mechanisms.
ER -
RAXWAL, Vivek Kumar and Karel ŘÍHA. The biological functions of nonsense-mediated mRNA decay in plants: RNA quality control and beyond. \textit{Biochemical Society Transactions}. London: Portland Press, 2023, vol.~51, No~1, p.~31-39. ISSN~0300-5127. Available from: https://dx.doi.org/10.1042/BST20211231.
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