J 2024

Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study

ŠTRUBLOVÁ, Lucie, Tomáš KEPÁK, Daniela KURUCZOVÁ, Filip ZLÁMAL, Marta HOLÍKOVÁ et. al.

Basic information

Original name

Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study

Name in Czech

Socioekonomický status a adipozita u dětí, které přežily rakovinu: Průřezová retrospektivní studie

Authors

ŠTRUBLOVÁ, Lucie (203 Czech Republic, guarantor, belonging to the institution), Tomáš KEPÁK (203 Czech Republic, belonging to the institution), Daniela KURUCZOVÁ (703 Slovakia), Filip ZLÁMAL (203 Czech Republic, belonging to the institution), Marta HOLÍKOVÁ (203 Czech Republic), Kateřina KEPÁKOVÁ (203 Czech Republic), Jaroslav ŠTĚRBA (203 Czech Republic, belonging to the institution) and Julie BIENERTOVÁ-VAŠKŮ (203 Czech Republic, belonging to the institution)

Edition

Plos One, SAN FRANCISCO, PUBLIC LIBRARY SCIENCE, 2024, 1932-6203

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.700 in 2022

Organization unit

Faculty of Medicine

UT WoS

001164078000040

Keywords in English

late effects of childhood cancer unemployment; adiposity; socioeconomic status; cancer survivorship

Tags

International impact, Reviewed
Změněno: 16/8/2024 07:47, Mgr. Tereza Miškechová

Abstract

V originále

This is a retrospective cross-sectional study examining the association between unemployment, cancer type, treatment and total body fat percentage of childhood cancer survivors recruited at St. Anne’s University Hospital in Brno, Czech Republic. A total of 55 survivors aged 18–49 who were in remission of cancer and fulfilled the criteria for body composition measurements by the BIA and completed questionnaires investigating their socioeconomic status, employment status, and history. There was a significant relationship between the employment status and central nervous system-directed treatment (χ2(1) = 7.53, p = 0.006, Cramér’s V = 0.38) and between the type of cancer and employment status (χ2(3) = 7.83, p = 0.049, Cramér’s V = 0.38), the highest unemployment rate was recorded for brain and spine survivors (72.7%) compared to survivors with other diagnosis (35.7%) (uLR(1) = 4.91, p = 0.027; OR = 4.80, 95% CI:1.10–20.86, p = 0.036); these survivors did not have a significantly different body fat percentage compared to survivors with other diagnoses (t(53) = 1.29, p = 0.202, Cohen’s d = 0.41) Interestingly, the survivors reporting having a partner also had a significantly higher percentage of body fat (t(53) = 2.90, p = 0.005, Cohen’s d = 0.81). A linear regression model was used to model the percentage of body fat in relation to a set of selected variables and the we observed a significant effect of sex (female vs male: b = 6.37, 95% CI: 1.82–10.93, p = 0.007), partnership status (yes vs no: b = 5.65, 95% CI: 0.67–10.62, p = 0.027) and category of diagnosis (Brain and spinal column tumors vs Other solid tumors: b = 12.40, 95% CI: 0.59–24.21, p = 0.040; Brain and spinal column tumors vs Lymphoma: b = 14.02, 95% CI: 2.06–25.97, p = 0.023). Employment status and risk of adiposity in childhood cancer survivors depends on the type of treatment and diagnosis group, which may significantly impact their lifestyle and overall quality of life after treatment.

Links

MUNI/A/1391/2021, interní kód MU
Name: Molekulární, buněčná, tkáňová a systémová patofyziologie vybraných komplexních nemocí (Acronym: KOMPLEX_PF)
Investor: Masaryk University