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@article{2376698,
author = {Petrášová, Martina and Šrotová, Iva and Kolčava, Jan and Štourač, Pavel and Hynková, Ludmila and Keřkovský, Miloš and Pikulová, Hana and Neuman, Eduard and Křen, Leoš and Vlčková, Eva},
article_location = {Lausanne},
article_number = {January 2024},
doi = {http://dx.doi.org/10.3389/fneur.2023.1324269},
keywords = {astrocytoma; multiple sclerosis; magnetic resonance imaging; positron-emission tomography; case report},
language = {eng},
issn = {1664-2295},
journal = {Frontiers in Neurology},
title = {Case report: Diagnostic challenge: a new multiple sclerosis "relapse" leading to the diagnosis of anaplastic astrocytoma},
url = {https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1324269/full},
volume = {14},
year = {2024}
}
TY - JOUR
ID - 2376698
AU - Petrášová, Martina - Šrotová, Iva - Kolčava, Jan - Štourač, Pavel - Hynková, Ludmila - Keřkovský, Miloš - Pikulová, Hana - Neuman, Eduard - Křen, Leoš - Vlčková, Eva
PY - 2024
TI - Case report: Diagnostic challenge: a new multiple sclerosis "relapse" leading to the diagnosis of anaplastic astrocytoma
JF - Frontiers in Neurology
VL - 14
IS - January 2024
SP - 1-6
EP - 1-6
PB - Frontiers
SN - 16642295
KW - astrocytoma
KW - multiple sclerosis
KW - magnetic resonance imaging
KW - positron-emission tomography
KW - case report
UR - https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1324269/full
N2 - Cerebral tumors and multiple sclerosis (MS) can show overlapping clinical and magnetic resonance imaging (MRI) features and even occur concurrently. Due to the emergence of new symptoms, not usually MS related, an MRI was conducted in a 29-year-old woman with relapsing-remitting MS and showed a significant size progression of a parieto-occipital lesion, with mild clinical correlates, such as blurred vision, difficulty in speaking, and headache. Contrast-enhanced MRI and fluorothymidine positron-emission tomography (PET) did not point toward neoplasm, a lesion biopsy, however, showed astrocytoma, which was confirmed as grade III astrocytoma after the radical resection of the tumor. In the case of an atypical lesion, a tumor should be considered in patients with MS. A small fraction of high-grade gliomas show no enhancement on MRI and no hypermetabolism on PET. Biopsy proved to be the essential step in a successful diagnostic workup. To the best of our knowledge, this is the first case of anaplastic astrocytoma with these radiological features reported in a patient with MS.
ER -
PETRÁŠOVÁ, Martina, Iva ŠROTOVÁ, Jan KOLČAVA, Pavel ŠTOURAČ, Ludmila HYNKOVÁ, Miloš KEŘKOVSKÝ, Hana PIKULOVÁ, Eduard NEUMAN, Leoš KŘEN and Eva VLČKOVÁ. Case report: Diagnostic challenge: a new multiple sclerosis ''relapse'' leading to the diagnosis of anaplastic astrocytoma. \textit{Frontiers in Neurology}. Lausanne: Frontiers, 2024, vol.~14, January 2024, p.~1-6. ISSN~1664-2295. Available from: https://dx.doi.org/10.3389/fneur.2023.1324269.
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