ELIXIR and Toxicology: a community in development [version 2;
peer review: 2 approved]

J 2023

ELIXIR and Toxicology: a community in development [version 2; peer review: 2 approved]

MARTENS, Marvin, Rob STIERUM, Emma L. SCHYMANSKI, Chris T. EVELO, Reza AALIZADEH et. al.

Basic information

Original name

ELIXIR and Toxicology: a community in development [version 2; peer review: 2 approved]

Authors

MARTENS, Marvin, Rob STIERUM, Emma L. SCHYMANSKI, Chris T. EVELO, Reza AALIZADEH, Hristo ALADJOV, Kasia ARTURI, Karine AUDOUZE, Pavel BABICA, Karel BERKA, Jos BESSEMS, Luděk BLÁHA, Evan E. BOLTON, Montserrat CASES, Dimitrios Ε. DAMALAS, Kirtan DAVE, Marco DILGER, Thomas EXNER, Daan P. GEERKE, Roland GRAFSTRÖM, Alasdair GRAY, John M. HANCOCK, Henner HOLLERT, Nina JELIAZKOVA, Danyel JENNEN, Fabien JOURDAN, Pascal KAHLEM, Jana KLÁNOVÁ, Jos KLEINJANS, Todor KONDIC, Boï KONE, Iseult LYNCH, Uko MARAN, Sergio Martinez CUESTA, Hervé MÉNAGER, Steffen NEUMANN, Penny NYMARK, Herbert OBERACHER, Noelia RAMIREZ, Sylvie REMY, Philippe ROCCA-SERRA, Reza M. SALEK, Brett SALLACH, Susanna-Assunta SANSONE, Ferran SANZ, Haralambos SARIMVEIS, Sirarat SARNTIVIJAI, Tobias SCHULZE, Jaroslav SLOBODNIK, Ola SPJUTH, Jonathan TEDDS, Nikolaos THOMAIDIS, Ralf J.M. WEBER, Gerard J.P. VAN WESTEN, Craig E. WHEELOCK, Antony J. WILLIAMS, Hilda WITTERS, Barbara ZDRAZIL and Anže ŽUPANIČ

Edition

F1000Research, F1000 Research Ltd, 2023, 2046-1402

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.12688/f1000research.74502.2

Keywords in English

ELIXIR; FAIR; interoperability; Toxicology

Změněno: 23/2/2024 10:41, Mgr. Marie Šípková, DiS.

Abstract

V originále

Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology, and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.

Links

733032, interní kód MU

Name: European Human Biomonitoring Initiative (Acronym: HBM4EU)

Investor: European Union, Health, demographic change and wellbeing (Societal Challenges)

825712, interní kód MU

Name: An integrative strategy of testing systems for identification of EDs related to metabolic disorders (Acronym: OBERON)

Investor: European Union, Health, demographic change and wellbeing (Societal Challenges)

859891, interní kód MU

Name: Best chemical risk assessment professionals for maximum Ecosystem Services benefit (Acronym: PRORISK)

Investor: European Union, MSCA Marie Skłodowska-Curie Actions (Excellent Science)

Citovat

@article{2377439,
   author = {Martens, Marvin and Stierum, Rob and Schymanski, Emma L. and Evelo, Chris T. and Aalizadeh, Reza and Aladjov, Hristo and Arturi, Kasia and Audouze, Karine and Babica, Pavel and Berka, Karel and Bessems, Jos and Bláha, Luděk and Bolton, Evan E. and Cases, Montserrat and Damalas, Dimitrios Ε. and Dave, Kirtan and Dilger, Marco and Exner, Thomas and Geerke, Daan P. and Grafström, Roland and Gray, Alasdair and Hancock, John M. and Hollert, Henner and Jeliazkova, Nina and Jennen, Danyel and Jourdan, Fabien and Kahlem, Pascal and Klánová, Jana and Kleinjans, Jos and Kondic, Todor and Kone, Boï and Lynch, Iseult and Maran, Uko and Cuesta, Sergio Martinez and Ménager, Hervé and Neumann, Steffen and Nymark, Penny and Oberacher, Herbert and Ramirez, Noelia and Remy, Sylvie and RoccaandSerra, Philippe and Salek, Reza M. and Sallach, Brett and Sansone, SusannaandAssunta and Sanz, Ferran and Sarimveis, Haralambos and Sarntivijai, Sirarat and Schulze, Tobias and Slobodnik, Jaroslav and Spjuth, Ola and Tedds, Jonathan and Thomaidis, Nikolaos and Weber, Ralf J.M. and van Westen, Gerard J.P. and Wheelock, Craig E. and Williams, Antony J. and Witters, Hilda and Zdrazil, Barbara and Županič, Anže},
   doi = {http://dx.doi.org/10.12688/f1000research.74502.2},
   keywords = {ELIXIR; FAIR; interoperability; Toxicology},
   language = {eng},
   issn = {2046-1402},
   journal = {F1000Research},
   title = {ELIXIR and Toxicology: a community in development [version 2; peer review: 2 approved]},
   url = {https://f1000research.com/articles/10-1129/v2},
   volume = {10},
   year = {2023}
}

TY  - JOUR
ID  - 2377439
AU  - Martens, Marvin - Stierum, Rob - Schymanski, Emma L. - Evelo, Chris T. - Aalizadeh, Reza - Aladjov, Hristo - Arturi, Kasia - Audouze, Karine - Babica, Pavel - Berka, Karel - Bessems, Jos - Bláha, Luděk - Bolton, Evan E. - Cases, Montserrat - Damalas, Dimitrios Ε. - Dave, Kirtan - Dilger, Marco - Exner, Thomas - Geerke, Daan P. - Grafström, Roland - Gray, Alasdair - Hancock, John M. - Hollert, Henner - Jeliazkova, Nina - Jennen, Danyel - Jourdan, Fabien - Kahlem, Pascal - Klánová, Jana - Kleinjans, Jos - Kondic, Todor - Kone, Boï - Lynch, Iseult - Maran, Uko - Cuesta, Sergio Martinez - Ménager, Hervé - Neumann, Steffen - Nymark, Penny - Oberacher, Herbert - Ramirez, Noelia - Remy, Sylvie - Rocca-Serra, Philippe - Salek, Reza M. - Sallach, Brett - Sansone, Susanna-Assunta - Sanz, Ferran - Sarimveis, Haralambos - Sarntivijai, Sirarat - Schulze, Tobias - Slobodnik, Jaroslav - Spjuth, Ola - Tedds, Jonathan - Thomaidis, Nikolaos - Weber, Ralf J.M. - van Westen, Gerard J.P. - Wheelock, Craig E. - Williams, Antony J. - Witters, Hilda - Zdrazil, Barbara - Županič, Anže
PY  - 2023
TI  - ELIXIR and Toxicology: a community in development [version 2; peer review: 2 approved]
JF  - F1000Research
VL  - 10
SP  - 1-24
EP  - 1-24
PB  - F1000 Research Ltd
SN  - 20461402
KW  - ELIXIR
KW  - FAIR
KW  - interoperability
KW  - Toxicology
UR  - https://f1000research.com/articles/10-1129/v2
N2  - Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology, and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.
ER  -

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