Pediatric neurovascular complication of SARS-CoV-2 infection: A
single Center Case-Series.

a 2023

Pediatric neurovascular complication of SARS-CoV-2 infection: A single Center Case-Series.

MUŽLAYOVÁ, Patrícia, Klára ŠPANĚLOVÁ, Tamara SKŘÍŠOVSKÁ, Ondřej HORÁK, Jan ŠENKYŘÍK et. al.

Basic information

Original name

Pediatric neurovascular complication of SARS-CoV-2 infection: A single Center Case-Series.

Authors

Edition

15th Congress of the European Pediatric Neurology Society (EPNS), Prague, 2023

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30209 Paediatrics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Organization unit

Faculty of Medicine

Keywords in English

Brain vasculopathy; COVID-19; Children; SARS-CoV-2; Stroke.

Změněno: 5/4/2024 10:12, Mgr. Tereza Miškechová

Abstract

V originále

SARS-CoV-2 virus causing Coronavirus disease 2019 (COVID-19) like other coronaviruses mainly targets the respiratory system. In symptomatic patients, the most common manifestation is fever, fatigue, cough, and headache. Severe forms can present with pneumonia, acute respiratory distress syndrome, acute cardiac dysfunction, and multiorgan failure. Some studies have indicated an association between COVID-19 and neurovascular conditions. These studies report mainly adult patients with a severe course of the infection. SARS-CoV-2 infects the host through its CoV spike glycoprotein, which binds to the angiotensin-converting enzyme 2 (ACE2) receptor, which is expressed in the lungs, heart, and kidneys and in endothelial cells. In general, pathophysiological processes after COVID-19 infection can cause vascular affliction and microvascular dysfunction and coagulation abnormalities. It is broadly believed that children usually have a mild case of SARS-CoV-2 infection. However, in connection with the prolong COVID-19 pandemic, we are more likely to see health conditions that have rarely been seen before and that share a common history of recent COVID-19. These cases are intended to present that the course of this infection may not always be benign and a longer period will be needed to assess the consequences of the infection. Further studies will certainly be needed to address the pathophysiological basis in an effort to ensure its optimal diagnostics and treatment in children. This article presents a case series of 3 children who were diagnosed with cerebrovascular disease and whose common denominator was current or previous infection with SARS-CoV-2

Citovat

MUŽLAYOVÁ, Patrícia, Klára ŠPANĚLOVÁ, Tamara SKŘÍŠOVSKÁ, Ondřej HORÁK, Jan ŠENKYŘÍK, Anna SEEHOFNEROVÁ, Lukáš HOMOLA, Jozef KLUČKA, Jan BLATNÝ, Hana OŠLEJŠKOVÁ and Pavlína DANHOFER. Pediatric neurovascular complication of SARS-CoV-2 infection: A single Center Case-Series. In 15th Congress of the European Pediatric Neurology Society (EPNS), Prague. 2023.

@proceedings{2379021,
   author = {Mužlayová, Patrícia and Španělová, Klára and Skříšovská, Tamara and Horák, Ondřej and Šenkyřík, Jan and Seehofnerová, Anna and Homola, Lukáš and Klučka, Jozef and Blatný, Jan and Ošlejšková, Hana and Danhofer, Pavlína},
   booktitle = {15th Congress of the European Pediatric Neurology Society (EPNS), Prague},
   keywords = {Brain vasculopathy; COVID-19; Children; SARS-CoV-2; Stroke.},
   language = {eng},
   title = {Pediatric neurovascular complication of SARS-CoV-2 infection: A single Center Case-Series.},
   url = {https://www.epns.info/wp-content/uploads/2023/06/EPNS23_Abstract_Book.pdf},
   year = {2023}
}

TY  - CONF
ID  - 2379021
AU  - Mužlayová, Patrícia - Španělová, Klára - Skříšovská, Tamara - Horák, Ondřej - Šenkyřík, Jan - Seehofnerová, Anna - Homola, Lukáš - Klučka, Jozef - Blatný, Jan - Ošlejšková, Hana - Danhofer, Pavlína
PY  - 2023
TI  - Pediatric neurovascular complication of SARS-CoV-2 infection: A single Center Case-Series.
KW  - Brain vasculopathy
KW  - COVID-19
KW  - Children
KW  - SARS-CoV-2
KW  - Stroke.
UR  - https://www.epns.info/wp-content/uploads/2023/06/EPNS23_Abstract_Book.pdf
N2  - SARS-CoV-2 virus causing Coronavirus disease 2019 (COVID-19) like other coronaviruses mainly targets the respiratory system. In symptomatic patients, the most common manifestation is fever, fatigue, cough, and headache. Severe forms can present with pneumonia, acute respiratory distress syndrome, acute cardiac dysfunction, and multiorgan failure. Some studies have indicated an association between COVID-19 and neurovascular conditions. These studies report mainly adult patients with a severe course of the infection. SARS-CoV-2 infects the host through its CoV spike glycoprotein, which binds to the angiotensin-converting enzyme 2 (ACE2) receptor, which is expressed in the lungs, heart, and kidneys and in endothelial cells. In general, pathophysiological processes after COVID-19 infection can cause vascular affliction and microvascular dysfunction and coagulation abnormalities. It is broadly believed that children usually have a mild case of SARS-CoV-2 infection. However, in connection with the prolong COVID-19 pandemic, we are more likely to see health conditions that have rarely been seen before and that share a common history of recent COVID-19. These cases are intended to present that the course of this infection may not always be benign and a longer period will be needed to assess the consequences of the infection. Further studies will certainly be needed to address the pathophysiological basis in an effort to ensure its optimal diagnostics and treatment in children. This article presents a case series of 3 children who were diagnosed with cerebrovascular disease and whose common denominator was current or previous infection with SARS-CoV-2
ER  -

MUŽLAYOVÁ, Patrícia, Klára ŠPANĚLOVÁ, Tamara SKŘÍŠOVSKÁ, Ondřej HORÁK, Jan ŠENKYŘÍK, Anna SEEHOFNEROVÁ, Lukáš HOMOLA, Jozef KLUČKA, Jan BLATNÝ, Hana OŠLEJŠKOVÁ and Pavlína DANHOFER. Pediatric neurovascular complication of SARS-CoV-2 infection: A single Center Case-Series. In \textit{15th Congress of the European Pediatric Neurology Society (EPNS), Prague}. 2023.

Detailed Information on Publication Record