| OLSOVSKA, Eva, Kristina CABANOVA, Oldrich MOTYKA, Hana BIELNIKOVA KRYSTOFOVA, Petra MATEJKOVA, Jirf VOVES, Vladimfr ZIDLIK, Roman MADEJA, Jiří DEMEL, Jan HALFAR and Jana KUKUTSCHOVA. Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study. Environmental Toxicology and Pharmacology. Amsterdam: Elsevier Science B.V., 2023, vol. 103, October 2023, p. 1-7. ISSN 1382-6689. Available from: https://dx.doi.org/10.1016/j.etap.2023.104282. |
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@article{2379129,
author = {Olsovska, Eva and Cabanova, Kristina and Motyka, Oldrich and Bielnikova Krystofova, Hana and Matejkova, Petra and Voves, Jirf and Zidlik, Vladimfr and Madeja, Roman and Demel, Jiří and Halfar, Jan and Kukutschova, Jana},
article_location = {Amsterdam},
article_number = {October 2023},
doi = {http://dx.doi.org/10.1016/j.etap.2023.104282},
keywords = {Traumatology; Biopsy samples; Metal-based particles; Automated analysis in the area; Scanning electron microscopy},
language = {eng},
issn = {1382-6689},
journal = {Environmental Toxicology and Pharmacology},
title = {Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study},
url = {https://www.sciencedirect.com/science/article/pii/S1382668923002247?via%3Dihub},
volume = {103},
year = {2023}
}
TY - JOUR
ID - 2379129
AU - Olsovska, Eva - Cabanova, Kristina - Motyka, Oldrich - Bielnikova Krystofova, Hana - Matejkova, Petra - Voves, Jirf - Zidlik, Vladimfr - Madeja, Roman - Demel, Jiří - Halfar, Jan - Kukutschova, Jana
PY - 2023
TI - Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study
JF - Environmental Toxicology and Pharmacology
VL - 103
IS - October 2023
SP - 1-7
EP - 1-7
PB - Elsevier Science B.V.
SN - 13826689
KW - Traumatology
KW - Biopsy samples
KW - Metal-based particles
KW - Automated analysis in the area
KW - Scanning electron microscopy
UR - https://www.sciencedirect.com/science/article/pii/S1382668923002247?via%3Dihub
N2 - The presence of particles fixed in tissue samples due to implant degradation or disintegration plays an important role in post-operative complications. The ability to determine the size, shape, chemical composition and, above all, the number of these particles can be used in many areas of medicine. This study presents a novel, simple metal-based particle detection method using scanning electron microscopy with energy dispersive spectrometer (SEM-EDS). The presence of metal particles in biopsy specimens from long bone nail-fixated implants (10 patients with titanium steel nails and 10 patients with stainless steel nails) was studied. The samples were analysed using automated area analysis based on image binarization and brightness to 255 grayscale. The results were supplemented with histological data and statistically analysed. The method based on the software used was found to be accurate and easy to use and, thus, appears to be very suitable for particle detection in similar samples.
ER -
OLSOVSKA, Eva, Kristina CABANOVA, Oldrich MOTYKA, Hana BIELNIKOVA KRYSTOFOVA, Petra MATEJKOVA, Jirf VOVES, Vladimfr ZIDLIK, Roman MADEJA, Jiří DEMEL, Jan HALFAR and Jana KUKUTSCHOVA. Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study. \textit{Environmental Toxicology and Pharmacology}. Amsterdam: Elsevier Science B.V., 2023, vol.~103, October 2023, p.~1-7. ISSN~1382-6689. Available from: https://dx.doi.org/10.1016/j.etap.2023.104282.
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