Simple method for quantification of metal-based particles in
biopsy samples of patients with long bone implants - Pilot
study

J 2023

Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study

OLSOVSKA, Eva, Kristina CABANOVA, Oldrich MOTYKA, Hana BIELNIKOVA KRYSTOFOVA, Petra MATEJKOVA et. al.

Basic information

Original name

Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study

Authors

OLSOVSKA, Eva (203 Czech Republic), Kristina CABANOVA (203 Czech Republic), Oldrich MOTYKA (203 Czech Republic), Hana BIELNIKOVA KRYSTOFOVA (203 Czech Republic), Petra MATEJKOVA (203 Czech Republic), Jirf VOVES (203 Czech Republic), Vladimfr ZIDLIK (203 Czech Republic), Roman MADEJA (203 Czech Republic), Jiří DEMEL (203 Czech Republic, belonging to the institution), Jan HALFAR (203 Czech Republic) and Jana KUKUTSCHOVA (203 Czech Republic)

Edition

Environmental Toxicology and Pharmacology, Amsterdam, Elsevier Science B.V. 2023, 1382-6689

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30212 Surgery

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.300 in 2022

RIV identification code

RIV/00216224:14110/23:00133659

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.etap.2023.104282

UT WoS

001097249400001

Keywords in English

Traumatology; Biopsy samples; Metal-based particles; Automated analysis in the area; Scanning electron microscopy

Abstract

V originále

The presence of particles fixed in tissue samples due to implant degradation or disintegration plays an important role in post-operative complications. The ability to determine the size, shape, chemical composition and, above all, the number of these particles can be used in many areas of medicine. This study presents a novel, simple metal-based particle detection method using scanning electron microscopy with energy dispersive spectrometer (SEM-EDS). The presence of metal particles in biopsy specimens from long bone nail-fixated implants (10 patients with titanium steel nails and 10 patients with stainless steel nails) was studied. The samples were analysed using automated area analysis based on image binarization and brightness to 255 grayscale. The results were supplemented with histological data and statistically analysed. The method based on the software used was found to be accurate and easy to use and, thus, appears to be very suitable for particle detection in similar samples.

Citovat

OLSOVSKA, Eva, Kristina CABANOVA, Oldrich MOTYKA, Hana BIELNIKOVA KRYSTOFOVA, Petra MATEJKOVA, Jirf VOVES, Vladimfr ZIDLIK, Roman MADEJA, Jiří DEMEL, Jan HALFAR and Jana KUKUTSCHOVA. Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study. Environmental Toxicology and Pharmacology. Amsterdam: Elsevier Science B.V., 2023, vol. 103, October 2023, p. 1-7. ISSN 1382-6689. Available from: https://dx.doi.org/10.1016/j.etap.2023.104282.

@article{2379129,
   author = {Olsovska, Eva and Cabanova, Kristina and Motyka, Oldrich and Bielnikova Krystofova, Hana and Matejkova, Petra and Voves, Jirf and Zidlik, Vladimfr and Madeja, Roman and Demel, Jiří and Halfar, Jan and Kukutschova, Jana},
   article_location = {Amsterdam},
   article_number = {October 2023},
   doi = {http://dx.doi.org/10.1016/j.etap.2023.104282},
   keywords = {Traumatology; Biopsy samples; Metal-based particles; Automated analysis in the area; Scanning electron microscopy},
   language = {eng},
   issn = {1382-6689},
   journal = {Environmental Toxicology and Pharmacology},
   title = {Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study},
   url = {https://www.sciencedirect.com/science/article/pii/S1382668923002247?via%3Dihub},
   volume = {103},
   year = {2023}
}

TY  - JOUR
ID  - 2379129
AU  - Olsovska, Eva - Cabanova, Kristina - Motyka, Oldrich - Bielnikova Krystofova, Hana - Matejkova, Petra - Voves, Jirf - Zidlik, Vladimfr - Madeja, Roman - Demel, Jiří - Halfar, Jan - Kukutschova, Jana
PY  - 2023
TI  - Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study
JF  - Environmental Toxicology and Pharmacology
VL  - 103
IS  - October 2023
SP  - 1-7
EP  - 1-7
PB  - Elsevier Science B.V.
SN  - 13826689
KW  - Traumatology
KW  - Biopsy samples
KW  - Metal-based particles
KW  - Automated analysis in the area
KW  - Scanning electron microscopy
UR  - https://www.sciencedirect.com/science/article/pii/S1382668923002247?via%3Dihub
N2  - The presence of particles fixed in tissue samples due to implant degradation or disintegration plays an important role in post-operative complications. The ability to determine the size, shape, chemical composition and, above all, the number of these particles can be used in many areas of medicine. This study presents a novel, simple metal-based particle detection method using scanning electron microscopy with energy dispersive spectrometer (SEM-EDS). The presence of metal particles in biopsy specimens from long bone nail-fixated implants (10 patients with titanium steel nails and 10 patients with stainless steel nails) was studied. The samples were analysed using automated area analysis based on image binarization and brightness to 255 grayscale. The results were supplemented with histological data and statistically analysed. The method based on the software used was found to be accurate and easy to use and, thus, appears to be very suitable for particle detection in similar samples.
ER  -

OLSOVSKA, Eva, Kristina CABANOVA, Oldrich MOTYKA, Hana BIELNIKOVA KRYSTOFOVA, Petra MATEJKOVA, Jirf VOVES, Vladimfr ZIDLIK, Roman MADEJA, Jiří DEMEL, Jan HALFAR and Jana KUKUTSCHOVA. Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study. \textit{Environmental Toxicology and Pharmacology}. Amsterdam: Elsevier Science B.V., 2023, vol.~103, October 2023, p.~1-7. ISSN~1382-6689. Available from: https://dx.doi.org/10.1016/j.etap.2023.104282.

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