J 2023

STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe

GREHN, Melanie, Stefano MANDIJA, Marcin MISZCZYK, David KRUG, Bartlomiej TOMASIK et. al.

Basic information

Original name

STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe

Authors

GREHN, Melanie, Stefano MANDIJA, Marcin MISZCZYK, David KRUG, Bartlomiej TOMASIK, Kristine E STICKNEY, Pino ALCANTARA, Filippo ALONGI, Matteo ANSELMINO, Ricardo Salgado ARANDA, Brian V BALGOBIND, Judit BODA-HEGGEMANN, Leif-Hendrik BOLDT, Nicola BOTTONI, Jakub CVEK, Olgun ELICIN, De Ferrari Gaetano MARIA, Rutger J HASSINK, Colien HAZELAAR, Gerhard HINDRICKS, Coen HURKMANS, Cinzia IOTTI, Tomasz JADCZYK, Otakar JIRAVSKÝ (203 Czech Republic, belonging to the institution), Raphaël JUMEAU, Steen Buus KRISTIANSEN, Mario LEVIS, Manuel Algara LOPEZ, Julio MARTI-ALMOR, Felix MEHRHOF, Ditte Sloth MOLLER, Giulio MOLON, Alexandre OUSS, Petr PEICHL, Jiri PLASEK, Pieter G POSTEMA, Aurelio QUESADA, Tobias REICHLIN, Roberto RORDORF, Boris RUDIC, Ardan M SAGUNER, Rachel M A TER BEKKE, Jose Lopez TORRECILLA, Esther G C TROOST, Viviana VITOLO, Nicolaus ANDRATSCHKE, Katja ZEPPENFELD, Slawomir BLAMEK, Martin FAST, de Panfilis LUDOVICA, Oliver BLANCK, Etienne PRUVOT and Joost J C VERHOEFF

Edition

EP Europace, Oxford, Oxford University Press, 2023, 1099-5129

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 6.100 in 2022

RIV identification code

RIV/00216224:14110/23:00133699

Organization unit

Faculty of Medicine

UT WoS

000951085000001

Keywords in English

Stereotactic arrhythmia radioablation; Ventricular tachycardia; Cardiac arrhythmias; Stereotactic body radiotherapy; Consortium; EU Horizon 2020

Tags

Tags

International impact, Reviewed
Změněno: 29/2/2024 12:29, Mgr. Tereza Miškechová

Abstract

V originále

The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research network for investigating STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia (VT). The aim is to provide a pooled treatment database to evaluate patterns of practice and outcomes of STAR and finally to harmonize STAR within Europe. The consortium comprises 31 clinical and research institutions. The project is divided into nine work packages (WPs): (i) observational cohort; (ii) standardization and harmonization of target delineation; (iii) harmonized prospective cohort; (iv) quality assurance (QA); (v) analysis and evaluation; (vi, ix) ethics and regulations; and (vii, viii) project coordination and dissemination. To provide a review of current clinical STAR practice in Europe, a comprehensive questionnaire was performed at project start. The STOPSTORM Institutions' experience in VT catheter ablation (83% >= 20 ann.) and stereotactic body radiotherapy (59% > 200 ann.) was adequate, and 84 STAR treatments were performed until project launch, while 8/22 centres already recruited VT patients in national clinical trials. The majority currently base their target definition on mapping during VT (96%) and/or pace mapping (75%), reduced voltage areas (63%), or late ventricular potentials (75%) during sinus rhythm. The majority currently apply a single-fraction dose of 25 Gy while planning techniques and dose prescription methods vary greatly. The current clinical STAR practice in the STOPSTORM consortium highlights potential areas of optimization and harmonization for substrate mapping, target delineation, motion management, dosimetry, and QA, which will be addressed in the various WPs.