STereotactic Arrhythmia Radioablation (STAR): the Standardized
Treatment and Outcome Platform for Stereotactic Therapy Of
Re-entrant tachycardia by a Multidisciplinary consortium
(STOPSTORM.eu) and review of current patterns of STAR practice
in Europe

J 2023

STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe

GREHN, Melanie, Stefano MANDIJA, Marcin MISZCZYK, David KRUG, Bartlomiej TOMASIK et. al.

Basic information

Original name

STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe

Authors

GREHN, Melanie, Stefano MANDIJA, Marcin MISZCZYK, David KRUG, Bartlomiej TOMASIK, Kristine E STICKNEY, Pino ALCANTARA, Filippo ALONGI, Matteo ANSELMINO, Ricardo Salgado ARANDA, Brian V BALGOBIND, Judit BODA-HEGGEMANN, Leif-Hendrik BOLDT, Nicola BOTTONI, Jakub CVEK, Olgun ELICIN, De Ferrari Gaetano MARIA, Rutger J HASSINK, Colien HAZELAAR, Gerhard HINDRICKS, Coen HURKMANS, Cinzia IOTTI, Tomasz JADCZYK, Otakar JIRAVSKÝ (203 Czech Republic, belonging to the institution), Raphaël JUMEAU, Steen Buus KRISTIANSEN, Mario LEVIS, Manuel Algara LOPEZ, Julio MARTI-ALMOR, Felix MEHRHOF, Ditte Sloth MOLLER, Giulio MOLON, Alexandre OUSS, Petr PEICHL, Jiri PLASEK, Pieter G POSTEMA, Aurelio QUESADA, Tobias REICHLIN, Roberto RORDORF, Boris RUDIC, Ardan M SAGUNER, Rachel M A TER BEKKE, Jose Lopez TORRECILLA, Esther G C TROOST, Viviana VITOLO, Nicolaus ANDRATSCHKE, Katja ZEPPENFELD, Slawomir BLAMEK, Martin FAST, de Panfilis LUDOVICA, Oliver BLANCK, Etienne PRUVOT and Joost J C VERHOEFF

Edition

EP Europace, Oxford, Oxford University Press, 2023, 1099-5129

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 6.100 in 2022

RIV identification code

RIV/00216224:14110/23:00133699

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1093/europace/euac238

UT WoS

000951085000001

Keywords in English

Stereotactic arrhythmia radioablation; Ventricular tachycardia; Cardiac arrhythmias; Stereotactic body radiotherapy; Consortium; EU Horizon 2020

Abstract

V originále

The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research network for investigating STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia (VT). The aim is to provide a pooled treatment database to evaluate patterns of practice and outcomes of STAR and finally to harmonize STAR within Europe. The consortium comprises 31 clinical and research institutions. The project is divided into nine work packages (WPs): (i) observational cohort; (ii) standardization and harmonization of target delineation; (iii) harmonized prospective cohort; (iv) quality assurance (QA); (v) analysis and evaluation; (vi, ix) ethics and regulations; and (vii, viii) project coordination and dissemination. To provide a review of current clinical STAR practice in Europe, a comprehensive questionnaire was performed at project start. The STOPSTORM Institutions' experience in VT catheter ablation (83% >= 20 ann.) and stereotactic body radiotherapy (59% > 200 ann.) was adequate, and 84 STAR treatments were performed until project launch, while 8/22 centres already recruited VT patients in national clinical trials. The majority currently base their target definition on mapping during VT (96%) and/or pace mapping (75%), reduced voltage areas (63%), or late ventricular potentials (75%) during sinus rhythm. The majority currently apply a single-fraction dose of 25 Gy while planning techniques and dose prescription methods vary greatly. The current clinical STAR practice in the STOPSTORM consortium highlights potential areas of optimization and harmonization for substrate mapping, target delineation, motion management, dosimetry, and QA, which will be addressed in the various WPs.

Citovat

GREHN, Melanie, Stefano MANDIJA, Marcin MISZCZYK, David KRUG, Bartlomiej TOMASIK, Kristine E STICKNEY, Pino ALCANTARA, Filippo ALONGI, Matteo ANSELMINO, Ricardo Salgado ARANDA, Brian V BALGOBIND, Judit BODA-HEGGEMANN, Leif-Hendrik BOLDT, Nicola BOTTONI, Jakub CVEK, Olgun ELICIN, De Ferrari Gaetano MARIA, Rutger J HASSINK, Colien HAZELAAR, Gerhard HINDRICKS, Coen HURKMANS, Cinzia IOTTI, Tomasz JADCZYK, Otakar JIRAVSKÝ, Raphaël JUMEAU, Steen Buus KRISTIANSEN, Mario LEVIS, Manuel Algara LOPEZ, Julio MARTI-ALMOR, Felix MEHRHOF, Ditte Sloth MOLLER, Giulio MOLON, Alexandre OUSS, Petr PEICHL, Jiri PLASEK, Pieter G POSTEMA, Aurelio QUESADA, Tobias REICHLIN, Roberto RORDORF, Boris RUDIC, Ardan M SAGUNER, Rachel M A TER BEKKE, Jose Lopez TORRECILLA, Esther G C TROOST, Viviana VITOLO, Nicolaus ANDRATSCHKE, Katja ZEPPENFELD, Slawomir BLAMEK, Martin FAST, de Panfilis LUDOVICA, Oliver BLANCK, Etienne PRUVOT and Joost J C VERHOEFF. STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe. EP Europace. Oxford: Oxford University Press, 2023, vol. 25, No 4, p. 1284-1295. ISSN 1099-5129. Available from: https://dx.doi.org/10.1093/europace/euac238.

@article{2379881,
   author = {Grehn, Melanie and Mandija, Stefano and Miszczyk, Marcin and Krug, David and Tomasik, Bartlomiej and Stickney, Kristine E and Alcantara, Pino and Alongi, Filippo and Anselmino, Matteo and Aranda, Ricardo Salgado and Balgobind, Brian V and BodaandHeggemann, Judit and Boldt, LeifandHendrik and Bottoni, Nicola and Cvek, Jakub and Elicin, Olgun and Maria, De Ferrari Gaetano and Hassink, Rutger J and Hazelaar, Colien and Hindricks, Gerhard and Hurkmans, Coen and Iotti, Cinzia and Jadczyk, Tomasz and Jiravský, Otakar and Jumeau, Raphaël and Kristiansen, Steen Buus and Levis, Mario and Lopez, Manuel Algara and MartiandAlmor, Julio and Mehrhof, Felix and Moller, Ditte Sloth and Molon, Giulio and Ouss, Alexandre and Peichl, Petr and Plasek, Jiri and Postema, Pieter G and Quesada, Aurelio and Reichlin, Tobias and Rordorf, Roberto and Rudic, Boris and Saguner, Ardan M and ter Bekke, Rachel M A and Torrecilla, Jose Lopez and Troost, Esther G C and Vitolo, Viviana and Andratschke, Nicolaus and Zeppenfeld, Katja and Blamek, Slawomir and Fast, Martin and Ludovica, de Panfilis and Blanck, Oliver and Pruvot, Etienne and Verhoeff, Joost J C},
   article_location = {Oxford},
   article_number = {4},
   doi = {http://dx.doi.org/10.1093/europace/euac238},
   keywords = {Stereotactic arrhythmia radioablation; Ventricular tachycardia; Cardiac arrhythmias; Stereotactic body radiotherapy; Consortium; EU Horizon 2020},
   language = {eng},
   issn = {1099-5129},
   journal = {EP Europace},
   title = {STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe},
   url = {https://academic.oup.com/europace/article/25/4/1284/7069964?login=true},
   volume = {25},
   year = {2023}
}

TY  - JOUR
ID  - 2379881
AU  - Grehn, Melanie - Mandija, Stefano - Miszczyk, Marcin - Krug, David - Tomasik, Bartlomiej - Stickney, Kristine E - Alcantara, Pino - Alongi, Filippo - Anselmino, Matteo - Aranda, Ricardo Salgado - Balgobind, Brian V - Boda-Heggemann, Judit - Boldt, Leif-Hendrik - Bottoni, Nicola - Cvek, Jakub - Elicin, Olgun - Maria, De Ferrari Gaetano - Hassink, Rutger J - Hazelaar, Colien - Hindricks, Gerhard - Hurkmans, Coen - Iotti, Cinzia - Jadczyk, Tomasz - Jiravský, Otakar - Jumeau, Raphaël - Kristiansen, Steen Buus - Levis, Mario - Lopez, Manuel Algara - Marti-Almor, Julio - Mehrhof, Felix - Moller, Ditte Sloth - Molon, Giulio - Ouss, Alexandre - Peichl, Petr - Plasek, Jiri - Postema, Pieter G - Quesada, Aurelio - Reichlin, Tobias - Rordorf, Roberto - Rudic, Boris - Saguner, Ardan M - ter Bekke, Rachel M A - Torrecilla, Jose Lopez - Troost, Esther G C - Vitolo, Viviana - Andratschke, Nicolaus - Zeppenfeld, Katja - Blamek, Slawomir - Fast, Martin - Ludovica, de Panfilis - Blanck, Oliver - Pruvot, Etienne - Verhoeff, Joost J C
PY  - 2023
TI  - STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe
JF  - EP Europace
VL  - 25
IS  - 4
SP  - 1284-1295
EP  - 1284-1295
PB  - Oxford University Press
SN  - 10995129
KW  - Stereotactic arrhythmia radioablation
KW  - Ventricular tachycardia
KW  - Cardiac arrhythmias
KW  - Stereotactic body radiotherapy
KW  - Consortium
KW  - EU Horizon 2020
UR  - https://academic.oup.com/europace/article/25/4/1284/7069964?login=true
N2  - The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research network for investigating STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia (VT). The aim is to provide a pooled treatment database to evaluate patterns of practice and outcomes of STAR and finally to harmonize STAR within Europe. The consortium comprises 31 clinical and research institutions. The project is divided into nine work packages (WPs): (i) observational cohort; (ii) standardization and harmonization of target delineation; (iii) harmonized prospective cohort; (iv) quality assurance (QA); (v) analysis and evaluation; (vi, ix) ethics and regulations; and (vii, viii) project coordination and dissemination. To provide a review of current clinical STAR practice in Europe, a comprehensive questionnaire was performed at project start. The STOPSTORM Institutions' experience in VT catheter ablation (83% >= 20 ann.) and stereotactic body radiotherapy (59% > 200 ann.) was adequate, and 84 STAR treatments were performed until project launch, while 8/22 centres already recruited VT patients in national clinical trials. The majority currently base their target definition on mapping during VT (96%) and/or pace mapping (75%), reduced voltage areas (63%), or late ventricular potentials (75%) during sinus rhythm. The majority currently apply a single-fraction dose of 25 Gy while planning techniques and dose prescription methods vary greatly. The current clinical STAR practice in the STOPSTORM consortium highlights potential areas of optimization and harmonization for substrate mapping, target delineation, motion management, dosimetry, and QA, which will be addressed in the various WPs.
ER  -

GREHN, Melanie, Stefano MANDIJA, Marcin MISZCZYK, David KRUG, Bartlomiej TOMASIK, Kristine E STICKNEY, Pino ALCANTARA, Filippo ALONGI, Matteo ANSELMINO, Ricardo Salgado ARANDA, Brian V BALGOBIND, Judit BODA-HEGGEMANN, Leif-Hendrik BOLDT, Nicola BOTTONI, Jakub CVEK, Olgun ELICIN, De Ferrari Gaetano MARIA, Rutger J HASSINK, Colien HAZELAAR, Gerhard HINDRICKS, Coen HURKMANS, Cinzia IOTTI, Tomasz JADCZYK, Otakar JIRAVSKÝ, Rapha$\backslash$''el JUMEAU, Steen Buus KRISTIANSEN, Mario LEVIS, Manuel Algara LOPEZ, Julio MARTI-ALMOR, Felix MEHRHOF, Ditte Sloth MOLLER, Giulio MOLON, Alexandre OUSS, Petr PEICHL, Jiri PLASEK, Pieter G POSTEMA, Aurelio QUESADA, Tobias REICHLIN, Roberto RORDORF, Boris RUDIC, Ardan M SAGUNER, Rachel M A TER BEKKE, Jose Lopez TORRECILLA, Esther G C TROOST, Viviana VITOLO, Nicolaus ANDRATSCHKE, Katja ZEPPENFELD, Slawomir BLAMEK, Martin FAST, de Panfilis LUDOVICA, Oliver BLANCK, Etienne PRUVOT and Joost J C VERHOEFF. STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe. \textit{EP Europace}. Oxford: Oxford University Press, 2023, vol.~25, No~4, p.~1284-1295. ISSN~1099-5129. Available from: https://dx.doi.org/10.1093/europace/euac238.

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