SPIELVOGEL, Clemens P, Stefan STOIBER, Laszlo PAPP, Denis KRAJNC, Marko GRAHOVAC, Elisabeth GURNHOFER, Karolína TRACHTOVÁ, Vojtěch BYSTRÝ, Asha LEISSER, Bernhard JANK, Julia SCHNOELL, Lorenz KADLETZ, Gregor HEIDUSCHKA, Thomas BEYER, Marcus HACKER, Lukas KENNER and Alexander R HAUG. Radiogenomic markers enable risk stratification and inference of mutational pathway states in head and neck cancer. European Journal of Nuclear Medicine and Molecular Imaging. NEW YORK: SPRINGER, 2023, vol. 50, No 2, p. 546-558. ISSN 1619-7070. Available from: https://dx.doi.org/10.1007/s00259-022-05973-9.
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Basic information
Original name Radiogenomic markers enable risk stratification and inference of mutational pathway states in head and neck cancer
Authors SPIELVOGEL, Clemens P, Stefan STOIBER, Laszlo PAPP, Denis KRAJNC, Marko GRAHOVAC, Elisabeth GURNHOFER, Karolína TRACHTOVÁ (203 Czech Republic, belonging to the institution), Vojtěch BYSTRÝ (203 Czech Republic, belonging to the institution), Asha LEISSER, Bernhard JANK, Julia SCHNOELL, Lorenz KADLETZ, Gregor HEIDUSCHKA, Thomas BEYER, Marcus HACKER, Lukas KENNER (guarantor) and Alexander R HAUG.
Edition European Journal of Nuclear Medicine and Molecular Imaging, NEW YORK, SPRINGER, 2023, 1619-7070.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30224 Radiology, nuclear medicine and medical imaging
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 9.100 in 2022
RIV identification code RIV/00216224:14740/23:00133757
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1007/s00259-022-05973-9
UT WoS 000859613300002
Keywords in English Head and neck cancer; Biomarkers; Radiomics; Machine learning; Artificial intelligence; Cancer genomics
Tags CF BIOIT, CF GEN, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Eva Dubská, učo 77638. Changed: 14/4/2024 13:00.
Abstract
Purpose Head and neck squamous cell carcinomas (HNSCCs) are a molecularly, histologically, and clinically heterogeneous set of tumors originating from the mucosal epithelium of the oral cavity, pharynx, and larynx. This heterogeneous nature of HNSCC is one of the main contributing factors to the lack of prognostic markers for personalized treatment. The aim of this study was to develop and identify multi-omics markers capable of improved risk stratification in this highly heterogeneous patient population.
Links
LM2023067, research and development projectName: Národní centrum lékařské genomiky
Investor: Ministry of Education, Youth and Sports of the CR, NCMG: The National Centre for Medical Genomic
90267, large research infrastructuresName: NCMG III
PrintDisplayed: 20/7/2024 09:23