DRUGS IN THE ENVIRONMENT

k 2023

DRUGS IN THE ENVIRONMENT

OPATŘILOVÁ, Radka

Basic information

Original name

DRUGS IN THE ENVIRONMENT

Name in Czech

Léčiva v životním prostřdí

Authors

OPATŘILOVÁ, Radka

Edition

51st Conference Synthesis and Analsis of Drugs, Bratislava, 2023

Other information

Language

English

Type of outcome

Prezentace na konferencích

Field of Study

30108 Toxicology

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Pharmacy

ISBN

978-80-280-0324-1

Abstract

V originále

Drugs of different chemical structures are becoming increasingly important potential environmental contaminants as pharmacotherapeutic options develop. Their effects on microorganisms, plants and animals are still being discovered and described. Drugs have been present in nature since they were first prepared synthetically. One of the first synthetic drugs is Acetylsalicylic acid (patent, Bayern, 1899). Its high consumption for treatment may have caused that as early as 1977 Acetylsalicylic acid was detected on the effluent of a sewage treatment plant (Missouri River), in an amount of 8.64 (0.55-28.69) kg over a 10-month period1 . Paracetamol has also been detected in the environment and is readily accumulated worldwide (concentrations in the units or tens of ng/l). Bacteria have already been described in the literature that are able to use Paracetamol as a carbon and energy source due to specialized systems and metabolic pathways2 . In contrast, studies3 have found that snakes die after consuming Paracetamol. World consumption of Diclofenac exceeds 2,400 tonnes per year. A study4 described renal and gastrointestinal disturbances in vertebrates. The authors5 described the extinction of up to 95% of the African vulture population after consumption of Diclofenac-treated livestock. Thanks to state-of-the-art instrumental methods, we can detect and quantify even ultra-low concentrations of pharmaceutical substances in the environment and study the influence of different chemical structures on environmental constituents. By setting up the right pharmaceutical management, we can then ensure a reduction in contamination and potential changes in a wide range of pharmaceuticals that we use in the context of our lifestyle.

Citovat

OPATŘILOVÁ, Radka. DRUGS IN THE ENVIRONMENT. In 51st Conference Synthesis and Analsis of Drugs, Bratislava. 2023. ISBN 978-80-280-0324-1.

@proceedings{2387758,
   author = {Opatřilová, Radka},
   booktitle = {51st Conference Synthesis and Analsis of Drugs, Bratislava},
   language = {eng},
   isbn = {978-80-280-0324-1},
   title = {DRUGS IN THE ENVIRONMENT},
   year = {2023}
}

TY  - CONF
ID  - 2387758
AU  - Opatřilová, Radka
PY  - 2023
TI  - DRUGS IN THE ENVIRONMENT
SN  - 9788028003241
N2  - Drugs of different chemical structures are becoming increasingly important potential environmental contaminants as pharmacotherapeutic options develop. Their effects on microorganisms, plants and animals are still being discovered and described. Drugs have been present in nature since they were first prepared synthetically. One of the first synthetic drugs is Acetylsalicylic acid (patent, Bayern, 1899). Its high consumption for treatment may have caused that as early as 1977 Acetylsalicylic acid was detected on the effluent of a sewage treatment plant (Missouri River), in an amount of 8.64 (0.55-28.69) kg over a 10-month period1 . Paracetamol has also been detected in the environment and is readily accumulated worldwide (concentrations in the units or tens of ng/l). Bacteria have already been described in the literature that are able to use Paracetamol as a carbon and energy source due to specialized systems and metabolic pathways2 . In contrast, studies3 have found that snakes die after consuming Paracetamol. World consumption of Diclofenac exceeds 2,400 tonnes per year. A study4 described renal and gastrointestinal disturbances in vertebrates. The authors5 described the extinction of up to 95% of the African vulture population after consumption of Diclofenac-treated livestock. Thanks to state-of-the-art instrumental methods, we can detect and quantify even ultra-low concentrations of pharmaceutical substances in the environment and study the influence of different chemical structures on environmental constituents. By setting up the right pharmaceutical management, we can then ensure a reduction in contamination and potential changes in a wide range of pharmaceuticals that we use in the context of our lifestyle.
ER  -

OPATŘILOVÁ, Radka. DRUGS IN THE ENVIRONMENT. In \textit{51st Conference Synthesis and Analsis of Drugs, Bratislava}. 2023. ISBN~978-80-280-0324-1.

Detailed Information on Publication Record