CVIKOVÁ, Martina, Jakub ŠTEFELA, Vít VŠIANSKÝ, Michal DUFEK, Irena DOLEŽALOVÁ, Jan VINKLÁREK, Roman HERZIG, Markéta ZEMANOVÁ, Vladimír ČERVEŇÁK, Jaroslav BRICHTA, Veronika BARKOVA, David KOURIL, Petr AULICKY, Pavel FILIP and Viktor WEISS. Case report: Susac syndrome-two ends of the spectrum, single center case reports and review of the literature. Frontiers in Neurology. Lausanne: Frontiers, 2024, vol. 15, February 2024, p. 1-10. ISSN 1664-2295. Available from: https://dx.doi.org/10.3389/fneur.2024.1339438.
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Basic information
Original name Case report: Susac syndrome-two ends of the spectrum, single center case reports and review of the literature
Authors CVIKOVÁ, Martina (703 Slovakia, belonging to the institution), Jakub ŠTEFELA (203 Czech Republic, belonging to the institution), Vít VŠIANSKÝ (203 Czech Republic, belonging to the institution), Michal DUFEK (203 Czech Republic, belonging to the institution), Irena DOLEŽALOVÁ (203 Czech Republic, belonging to the institution), Jan VINKLÁREK (203 Czech Republic, belonging to the institution), Roman HERZIG (203 Czech Republic), Markéta ZEMANOVÁ (203 Czech Republic, belonging to the institution), Vladimír ČERVEŇÁK (203 Czech Republic, belonging to the institution), Jaroslav BRICHTA (203 Czech Republic, belonging to the institution), Veronika BARKOVA (203 Czech Republic), David KOURIL (203 Czech Republic), Petr AULICKY (203 Czech Republic), Pavel FILIP (703 Slovakia) and Viktor WEISS (203 Czech Republic, belonging to the institution).
Edition Frontiers in Neurology, Lausanne, Frontiers, 2024, 1664-2295.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.400 in 2022
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3389/fneur.2024.1339438
UT WoS 001175679000001
Keywords in English Susac syndrome; vasculitis; branch retinal arterial occlusion; stroke; neuroimmunology; black blood imaging; hearing loss
Tags 14110119, 14110127
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 29/4/2024 13:46.
Abstract
Susac syndrome is a rare and enigmatic complex neurological disorder primarily affecting small blood vessels in the brain, retina, and inner ear. Diagnosing Susac syndrome may be extremely challenging not only due to its rarity, but also due to the variability of its clinical presentation. This paper describes two vastly different cases-one with mild symptoms and good response to therapy, the other with severe, complicated course, relapses and long-term sequelae despite multiple therapeutic interventions. Building upon the available guidelines, we highlight the utility of black blood MRI in this disease and provide a comprehensive review of available clinical experience in clinical presentation, diagnosis and therapy of this disease. Despite its rarity, the awareness of Susac syndrome may be of uttermost importance since it ultimately is a treatable condition. If diagnosed in a timely manner, early intervention can substantially improve the outcomes of our patients.
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