Direct mailing of HPV self-sampling kits to women aged 50-65
non-participating in cervical screening in the Czech Republic

J 2024

Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic

NGO, Ondřej, Renata CHLOUPKOVÁ, David CIBULA, Jiri SLAMA, Lucie MANDELOVA et. al.

Basic information

Original name

Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic

Authors

NGO, Ondřej (203 Czech Republic, belonging to the institution), Renata CHLOUPKOVÁ (203 Czech Republic, belonging to the institution), David CIBULA (203 Czech Republic), Jiri SLAMA (203 Czech Republic), Lucie MANDELOVA (203 Czech Republic), Karel HEJDUK (203 Czech Republic, belonging to the institution), Marian HAJDUCH (203 Czech Republic), Petr MINKA (203 Czech Republic), Vladimira KOUDELAKOVA (203 Czech Republic), Hana JAWOREK (203 Czech Republic), Marketa TRNKOVA (203 Czech Republic), Peter VANEK (203 Czech Republic), Vladimir DVORAK (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic, belonging to the institution) and Ondřej MÁJEK (203 Czech Republic, belonging to the institution)

Edition

European journal of public health, OXFORD, OXFORD UNIV PRESS, 2024, 1101-1262

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30214 Obstetrics and gynaecology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.400 in 2022

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1093/eurpub/ckad229

UT WoS

001147898300001

Keywords in English

cervical screening; HPV self-sampling kits; Czech Republic

Abstract

V originále

Background: A population-based cervical cancer screening programme is implemented in the Czech Republic. However, participation is insufficient among women over 50 years. This study aimed to estimate the potential improvement in participation through directly mailed HPV self-sampling kits (HPVssk) compared with standard invitation letters in women aged 50-65 non-participating in screening.Methods: The study recruited 1564 eligible women (no cervical cancer screening in the last 3 years or more, no previous treatment associated with cervical lesions or cervical cancer). Eight hundred women were mailed with an HPVssk (HPVssk group), and 764 women were sent a standard invitation letter (control group) inviting them to a routine screening (Pap test). The primary outcome was a comparison of the overall participation rate between study groups using a binominal regression model.Results: The participation rate in the HPVssk group was 13.4% [95% confidence interval (CI) 11.2-15.9%; 7.4% of women returned the HPVssk and 6.0% attended gynaecological examination] and 5.0% (95% CI 3.6-6.8%) in the control group. Using the binominal regression model, the difference between the groups was estimated as 7.6% (95% CI 5.0-10.2%; P < 0.001). In the HPVssk group, 22% of women who returned HPVssk had a positive result and 70% of them underwent a follow-up examination.Conclusions: Compared with traditional invitation letters, the direct mailing of the HPVssk achieved a significantly higher participation rate, along with a notable HPV positivity rate among HPVssk responders. This approach offers a potentially viable method for engaging women who have not yet attended a cervical screening programme.

Links

EF16_013/0001818, research and development project

Name: Modernizace a podpora výzkumných aktivit národní infrastruktury pro translační medicínu EATRIS-CZ

Citovat

NGO, Ondřej, Renata CHLOUPKOVÁ, David CIBULA, Jiri SLAMA, Lucie MANDELOVA, Karel HEJDUK, Marian HAJDUCH, Petr MINKA, Vladimira KOUDELAKOVA, Hana JAWOREK, Marketa TRNKOVA, Peter VANEK, Vladimir DVORAK, Ladislav DUŠEK and Ondřej MÁJEK. Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic. European journal of public health. OXFORD: OXFORD UNIV PRESS, 2024, vol. 34, No 2, p. 361-367. ISSN 1101-1262. Available from: https://dx.doi.org/10.1093/eurpub/ckad229.

@article{2398800,
   author = {Ngo, Ondřej and Chloupková, Renata and Cibula, David and Slama, Jiri and Mandelova, Lucie and Hejduk, Karel and Hajduch, Marian and Minka, Petr and Koudelakova, Vladimira and Jaworek, Hana and Trnkova, Marketa and Vanek, Peter and Dvorak, Vladimir and Dušek, Ladislav and Májek, Ondřej},
   article_location = {OXFORD},
   article_number = {2},
   doi = {http://dx.doi.org/10.1093/eurpub/ckad229},
   keywords = {cervical screening; HPV self-sampling kits; Czech Republic},
   language = {eng},
   issn = {1101-1262},
   journal = {European journal of public health},
   title = {Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic},
   url = {https://academic.oup.com/eurpub/article/34/2/361/7542404?login=true},
   volume = {34},
   year = {2024}
}

TY  - JOUR
ID  - 2398800
AU  - Ngo, Ondřej - Chloupková, Renata - Cibula, David - Slama, Jiri - Mandelova, Lucie - Hejduk, Karel - Hajduch, Marian - Minka, Petr - Koudelakova, Vladimira - Jaworek, Hana - Trnkova, Marketa - Vanek, Peter - Dvorak, Vladimir - Dušek, Ladislav - Májek, Ondřej
PY  - 2024
TI  - Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic
JF  - European journal of public health
VL  - 34
IS  - 2
SP  - 361-367
EP  - 361-367
PB  - OXFORD UNIV PRESS
SN  - 11011262
KW  - cervical screening
KW  - HPV self-sampling kits
KW  - Czech Republic
UR  - https://academic.oup.com/eurpub/article/34/2/361/7542404?login=true
N2  - Background: A population-based cervical cancer screening programme is implemented in the Czech Republic. However, participation is insufficient among women over 50 years. This study aimed to estimate the potential improvement in participation through directly mailed HPV self-sampling kits (HPVssk) compared with standard invitation letters in women aged 50-65 non-participating in screening.Methods: The study recruited 1564 eligible women (no cervical cancer screening in the last 3 years or more, no previous treatment associated with cervical lesions or cervical cancer). Eight hundred women were mailed with an HPVssk (HPVssk group), and 764 women were sent a standard invitation letter (control group) inviting them to a routine screening (Pap test). The primary outcome was a comparison of the overall participation rate between study groups using a binominal regression model.Results: The participation rate in the HPVssk group was 13.4% [95% confidence interval (CI) 11.2-15.9%; 7.4% of women returned the HPVssk and 6.0% attended gynaecological examination] and 5.0% (95% CI 3.6-6.8%) in the control group. Using the binominal regression model, the difference between the groups was estimated as 7.6% (95% CI 5.0-10.2%; P < 0.001). In the HPVssk group, 22% of women who returned HPVssk had a positive result and 70% of them underwent a follow-up examination.Conclusions: Compared with traditional invitation letters, the direct mailing of the HPVssk achieved a significantly higher participation rate, along with a notable HPV positivity rate among HPVssk responders. This approach offers a potentially viable method for engaging women who have not yet attended a cervical screening programme.
ER  -

NGO, Ondřej, Renata CHLOUPKOVÁ, David CIBULA, Jiri SLAMA, Lucie MANDELOVA, Karel HEJDUK, Marian HAJDUCH, Petr MINKA, Vladimira KOUDELAKOVA, Hana JAWOREK, Marketa TRNKOVA, Peter VANEK, Vladimir DVORAK, Ladislav DUŠEK and Ondřej MÁJEK. Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic. \textit{European journal of public health}. OXFORD: OXFORD UNIV PRESS, 2024, vol.~34, No~2, p.~361-367. ISSN~1101-1262. Available from: https://dx.doi.org/10.1093/eurpub/ckad229.

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