a 2022

Dynamics of fMRI connectivity associated with attention in patients with Parkinson’s disease

GAJDOŠ, Martin, Kristína MITTEROVÁ, Martin LAMOŠ and Irena REKTOROVÁ

Basic information

Original name

Dynamics of fMRI connectivity associated with attention in patients with Parkinson’s disease

Authors

GAJDOŠ, Martin (203 Czech Republic, guarantor, belonging to the institution), Kristína MITTEROVÁ (703 Slovakia, belonging to the institution), Martin LAMOŠ (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, belonging to the institution)

Edition

OHBM 2022 Annual Meeting, Glasgow, 2022

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30103 Neurosciences

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Organization unit

Central European Institute of Technology

Keywords in English

fMRI; Parkinson’s disease; independent component analysis; sliding window analysis

Tags

Tags

International impact, Reviewed
Změněno: 22/8/2024 14:31, Mgr. Eva Dubská

Abstract

V originále

Dynamic fMRI connectivity extends information reported with static fMRI connectivity. In this work, we focused on relation between changes in brain states and behavioral characteristics in patients with Parkinson’s disease (PD). Our dataset consists of 31 patients with PD (age 63.1 ± 10.2, 7 women) and 40 HC (age 66.0 ± 7.7 let, 29 women). We used independent component analysis (ICA) in toolbox GIFT for identification of large scale brain networks. We performed sliding window analysis on timeseries of mentioned ICA components. We observed statistically significant differences in dynamic parameters, probably relevant to preparation attentional activity of top-down type.

Links

NU21J-04-00077, research and development project
Name: Využití dynamických parametrů funkční konektivity mozku jako diagnostického biomarkeru neurodegenerativních nemocí
Investor: Ministry of Health of the CR, Biomarkers of neurodegenerative diseases based on dynamic functional connectivity, Subprogram 2 - junior