Dynamics of fMRI connectivity associated with attention in patients with Parkinson’s disease

GAJDOŠ, Martin, Kristína MITTEROVÁ, Martin LAMOŠ and Irena REKTOROVÁ. Dynamics of fMRI connectivity associated with attention in patients with Parkinson’s disease. In OHBM 2022 Annual Meeting, Glasgow. 2022.

Basic information

• Original name: Dynamics of fMRI connectivity associated with attention in patients with Parkinson’s disease
• Authors: GAJDOŠ, Martin, Kristína MITTEROVÁ, Martin LAMOŠ and Irena REKTOROVÁ.
• Edition: OHBM 2022 Annual Meeting, Glasgow, 2022.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 30103 Neurosciences
• Country of publisher: United Kingdom of Great Britain and Northern Ireland
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Organization unit: Central European Institute of Technology
• Tags: CF MAFIL
• Tags: International impact, Reviewed

Abstract

Dynamic fMRI connectivity extends information reported with static fMRI connectivity. In this work, we focused on relation between changes in brain states and behavioral characteristics in patients with Parkinson’s disease (PD). Our dataset consists of 31 patients with PD (age 63.1 ± 10.2, 7 women) and 40 HC (age 66.0 ± 7.7 let, 29 women). We used independent component analysis (ICA) in toolbox GIFT for identification of large scale brain networks. We performed sliding window analysis on timeseries of mentioned ICA components. We observed statistically significant differences in dynamic parameters, probably relevant to preparation attentional activity of top-down type.

Links

• NU21J-04-00077, research and development project: Name: Využití dynamických parametrů funkční konektivity mozku jako diagnostického biomarkeru neurodegenerativních nemocí

Investor: Ministry of Health of the CR, Biomarkers of neurodegenerative diseases based on dynamic functional connectivity, Subprogram 2 - junior