a 2024

Determination of metal ion levels in circulation in patients with joint replacement

VÁLKOVÁ, Lucie, Jan EMMER, Jan KUTA and Monika PÁVKOVÁ GOLDBERGOVÁ

Basic information

Original name

Determination of metal ion levels in circulation in patients with joint replacement

Authors

VÁLKOVÁ, Lucie (203 Czech Republic, belonging to the institution), Jan EMMER (203 Czech Republic), Jan KUTA (203 Czech Republic, belonging to the institution) and Monika PÁVKOVÁ GOLDBERGOVÁ (203 Czech Republic, belonging to the institution)

Edition

ExcellMater Conference 2024: Innovative biomaterials for novel medical devices, 2024

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30211 Orthopaedics

Country of publisher

Serbia

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Organization unit

Faculty of Medicine

Keywords in English

joint replacement; metal ion levels; circulation

Tags

International impact
Změněno: 21/8/2024 10:34, Mgr. Tereza Miškechová

Abstract

V originále

In the past century, total joint arthroplasty has been recognized as one of the most successful and effective orthopaedic procedures. This approach, which treats mostly hip and knee joint disorders, may reduce pain, correct deformity, and improve the patient's quality of life. Materials of choice for orthopaedic implants include stainless steel, cobalt-chromium alloys, and titanium alloys. When using a metal implant, some degree of material degradation is unavoidable, which can cause issues for the patient. Various factors leading to implant deterioration are expected to result in the release of nanoparticles or ions, which can cause loosening and osteolysis. The release of oxides and metal ions can be detectable within the first few days after the alloy implantation. The tissue surrounding the implants can collect dissolved metal ions, or the ions can be discharged into bloodstream and accumulate in distant organs. The present study is focused on monitoring metal ions released from implanted material into circulation.

Links

LM2023069, research and development project
Name: Výzkumná infrastruktura RECETOX
Investor: Ministry of Education, Youth and Sports of the CR, RECETOX research infrastructure
NU20-08-00149, research and development project
Name: Multicentrické hodnocení hypersenzitivní reakce u pacientů indikovaných k totální náhradě kloubu včetně hodnocení důvodů reimplanace
Investor: Ministry of Health of the CR, Subprogram 1 - standard