J 2024

Intra-Individual Relationship between Heart Rate Variability and the Underlying Heart Rate in Children and Adolescents

ŠIŠÁKOVÁ, Martina, Kateřina HELÁNOVÁ, Katerina HNATKOVA, Irena ANDRŠOVÁ, Tomáš NOVOTNÝ et. al.

Basic information

Original name

Intra-Individual Relationship between Heart Rate Variability and the Underlying Heart Rate in Children and Adolescents

Authors

ŠIŠÁKOVÁ, Martina (203 Czech Republic, belonging to the institution), Kateřina HELÁNOVÁ (203 Czech Republic, belonging to the institution), Katerina HNATKOVA (203 Czech Republic), Irena ANDRŠOVÁ (203 Czech Republic, belonging to the institution), Tomáš NOVOTNÝ (203 Czech Republic, belonging to the institution) and Marek MALÍK (203 Czech Republic, belonging to the institution)

Edition

Journal of Clinical Medicine, Basel, MDPI, 2024, 2077-0383

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.900 in 2022

Organization unit

Faculty of Medicine

DOI

UT WoS

001233553900001

Keywords in English

paediatric population; heart rate variability; heart rate; regression slope; age; sympatho-vagal balance

Tags

Tags

International impact, Reviewed
Změněno: 5/6/2024 09:29, Mgr. Tereza Miškechová

Abstract

V originále

Background/Objective: The relationship between heart rate and heart rate variability (HRV) indices has been repeatedly studied in adults but limited data are available on the relationship in paediatric populations. Methods: Continuous 12-lead electrocardiograms were recorded in 1016 healthy children and adolescents (534 females) aged 4 to 19 years during postural manoeuvres with rapid changes between 10-min positions of supine -> sitting -> standing -> supine -> standing -> sitting -> supine. In each position, the averaged RR interval was measured together with four HRV indices, namely the SDNN, RMSSD, quasi-normalised high-frequency components (qnHF), and the proportions of low- and high-frequency components (LF/HF). In each subject, the slope of the linear regression between the repeated HRV measurements and the corresponding RR interval averages was calculated. Results: The intra-subject regression slopes, including their confidence intervals, were related to the age and sex of the subjects. The SDNN/RR, RMSSD/RR, and qnHF/RR slopes were significantly steeper (p < 0.001) and the (LF/HF)/RR slopes were significantly shallower (p < 0.001) in younger children compared to older children and adolescents. Conclusions: The study suggests that sympathetic and vagal influences on heart rate are present in both younger and older children. With advancing age, the sympatho-vagal balance gradually develops and allows the vagal control to suppress the sympathetic drive towards higher heart rates seen in younger age children.