HORÁK, Tomáš, Magda HORÁKOVÁ, Miloš KEŘKOVSKÝ, Marek DOSTÁL, Petr HLUSTIK, Jan VALOSEK, Alena SVATKOVA, Petr BEDNARIK, Eva VLČKOVÁ and Josef BEDNAŘÍK. Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy. Frontiers in Neurology. Lausanne: Frontiers, 2024, vol. 15, May 2024, p. 1-9. ISSN 1664-2295. Available from: https://dx.doi.org/10.3389/fneur.2024.1341371.
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Basic information
Original name Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy
Authors HORÁK, Tomáš (203 Czech Republic, belonging to the institution), Magda HORÁKOVÁ (203 Czech Republic, belonging to the institution), Miloš KEŘKOVSKÝ (203 Czech Republic, belonging to the institution), Marek DOSTÁL (203 Czech Republic, belonging to the institution), Petr HLUSTIK (203 Czech Republic), Jan VALOSEK (203 Czech Republic), Alena SVATKOVA (203 Czech Republic), Petr BEDNARIK (203 Czech Republic), Eva VLČKOVÁ (203 Czech Republic, belonging to the institution) and Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution).
Edition Frontiers in Neurology, Lausanne, Frontiers, 2024, 1664-2295.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.400 in 2022
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3389/fneur.2024.1341371
UT WoS 001229861800001
Keywords in English degenerative cervical cord compression; degenerative cervical myelopathy; cervical spinal canal stenosis; magnetic resonance imaging; subclinical myelopathy
Tags 14110216, 14110221, 14110511, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 5/6/2024 14:21.
Abstract
Degenerative cervical myelopathy (DCM) represents the final consequence of a series of degenerative changes in the cervical spine, resulting in cervical spinal canal stenosis and mechanical stress on the cervical spinal cord. This process leads to subsequent pathophysiological processes in the spinal cord tissues. The primary mechanism of injury is degenerative compression of the cervical spinal cord, detectable by magnetic resonance imaging (MRI), serving as a hallmark for diagnosing DCM. However, the relative resilience of the cervical spinal cord to mechanical compression leads to clinical-radiological discordance, i.e., some individuals may exhibit MRI findings of DCC without the clinical signs and symptoms of myelopathy. This degenerative compression of the cervical spinal cord without clinical signs of myelopathy, potentially serving as a precursor to the development of DCM, remains a somewhat controversial topic. In this review article, we elaborate on and provide commentary on the terminology, epidemiology, natural course, diagnosis, predictive value, risks, and practical management of this condition-all of which are subjects of ongoing debate.
Links
NU22-04-00024, research and development projectName: Kvantitativní zobrazovací MR parametry jako prediktory průběhu nemyelopatické degenerativní komprese krční míchy: longitudinální studie
Investor: Ministry of Health of the CR, Quantitative magnetic resonance imaging parameters as predictors of outcome of non-myelopathic degenerative cervical cord compression: a longitudinal study, Subprogram 1 - standard
PrintDisplayed: 17/7/2024 01:53