BISKUPIČ, Jan, Marcela VLČNOVSKÁ, Jana HLOŽKOVÁ, Peter SCHEER, Tereza PADRTOVÁ, Radka OPATŘILOVÁ, Viktor KANICKÝ, Tomáš VACULOVIČ and Michaela KUCHYNKA. NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND TREATMENT OF ISCHEMIC STROKE. In Student Scientific Conference MUNI Pharm. 2023. ISBN 978-80-280-0323-4.
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Basic information
Original name NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND TREATMENT OF ISCHEMIC STROKE
Authors BISKUPIČ, Jan, Marcela VLČNOVSKÁ, Jana HLOŽKOVÁ, Peter SCHEER, Tereza PADRTOVÁ, Radka OPATŘILOVÁ, Viktor KANICKÝ, Tomáš VACULOVIČ and Michaela KUCHYNKA.
Edition Student Scientific Conference MUNI Pharm, 2023.
Other information
Original language English
Type of outcome Presentations at conferences
Field of Study 10406 Analytical chemistry
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Organization unit Faculty of Science
ISBN 978-80-280-0323-4
Keywords (in Czech) biologické zobrazování; laserová ablace; prvková distribuce
Keywords in English Bioimaging; laser ablation; element distribution
Tags ÚCh, ÚChL, ÚFTo
Tags Reviewed
Changed by Changed by: Mgr. Michaela Kuchynka, Ph.D., učo 358018. Changed: 6/6/2024 15:52.
Abstract
Ischemic stroke (IS) was identified as the second most common cause of death worldwide in 2019 according to a survey [1]. A large percentage of patients remain with permanent consequences that can persist even fifteen years after the event [2]. This is also associated with economic impacts on healthcare and supportive services, which amounted to approximately 60 billion euros in the EU in 2017 [3]. The key to success is time. IS can already be precisely diagnosed nowadays. However, in each specific situation, there is a problem with detecting the onset of stroke, which is crucial for choosing the appropriate treatment and thus saving lives. Today’s commonly used medical scanning devices can only visualize clots with high erythrocyte content. Other forms of thrombi become very difficult to recognize [4]. Polyiodinated biodegradable nanoparticles (IoNPs) have the potential to solve this problem. The current preclinical phase of our project is focused on researching the pharmacokinetics of these potential IoNPs theranostics in the body. A unique method LA-ICP-MS is used to determine the IoNPs distribution. The study was supported by Grant Agency of Masaryk University – Excellent diploma thesis, MUNI/C/0002/2023.
Links
MUNI/C/0002/2023, interní kód MUName: Nanočástice jako nový nástroj pro diagnostiku a léčbu cévní mozkové příhody
Investor: Masaryk University, Nanoparticles as a new tool for the diagnosis and treatment of ischemic stroke, Excellent diploma thesis
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