NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND  TREATMENT OF
ISCHEMIC STROKE

k 2023

NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND TREATMENT OF ISCHEMIC STROKE

BISKUPIČ, Jan, Marcela VLČNOVSKÁ, Jana HLOŽKOVÁ, Peter SCHEER, Tereza PADRTOVÁ et. al.

Basic information

Original name

NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND TREATMENT OF ISCHEMIC STROKE

Authors

BISKUPIČ, Jan, Marcela VLČNOVSKÁ, Jana HLOŽKOVÁ, Peter SCHEER, Tereza PADRTOVÁ, Radka OPATŘILOVÁ, Viktor KANICKÝ, Tomáš VACULOVIČ and Michaela KUCHYNKA

Edition

Student Scientific Conference MUNI Pharm, 2023

Other information

Language

English

Type of outcome

Prezentace na konferencích

Field of Study

10406 Analytical chemistry

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Organization unit

Faculty of Science

ISBN

978-80-280-0323-4

Keywords (in Czech)

biologické zobrazování; laserová ablace; prvková distribuce

Keywords in English

Bioimaging; laser ablation; element distribution

Abstract

V originále

Ischemic stroke (IS) was identified as the second most common cause of death worldwide in 2019 according to a survey [1]. A large percentage of patients remain with permanent consequences that can persist even fifteen years after the event [2]. This is also associated with economic impacts on healthcare and supportive services, which amounted to approximately 60 billion euros in the EU in 2017 [3]. The key to success is time. IS can already be precisely diagnosed nowadays. However, in each specific situation, there is a problem with detecting the onset of stroke, which is crucial for choosing the appropriate treatment and thus saving lives. Today’s commonly used medical scanning devices can only visualize clots with high erythrocyte content. Other forms of thrombi become very difficult to recognize [4]. Polyiodinated biodegradable nanoparticles (IoNPs) have the potential to solve this problem. The current preclinical phase of our project is focused on researching the pharmacokinetics of these potential IoNPs theranostics in the body. A unique method LA-ICP-MS is used to determine the IoNPs distribution. The study was supported by Grant Agency of Masaryk University – Excellent diploma thesis, MUNI/C/0002/2023.

Links

MUNI/C/0002/2023, interní kód MU

Name: Nanočástice jako nový nástroj pro diagnostiku a léčbu cévní mozkové příhody

Investor: Masaryk University, Nanoparticles as a new tool for the diagnosis and treatment of ischemic stroke, Excellent diploma thesis

Citovat

BISKUPIČ, Jan, Marcela VLČNOVSKÁ, Jana HLOŽKOVÁ, Peter SCHEER, Tereza PADRTOVÁ, Radka OPATŘILOVÁ, Viktor KANICKÝ, Tomáš VACULOVIČ and Michaela KUCHYNKA. NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND TREATMENT OF ISCHEMIC STROKE. In Student Scientific Conference MUNI Pharm. 2023. ISBN 978-80-280-0323-4.

@proceedings{2408377,
   author = {Biskupič, Jan and Vlčnovská, Marcela and Hložková, Jana and Scheer, Peter and Padrtová, Tereza and Opatřilová, Radka and Kanický, Viktor and Vaculovič, Tomáš and Kuchynka, Michaela},
   booktitle = {Student Scientific Conference MUNI Pharm},
   keywords = {Bioimaging; laser ablation; element distribution},
   language = {eng},
   isbn = {978-80-280-0323-4},
   title = {NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND TREATMENT OF ISCHEMIC STROKE},
   url = {https://www.pharm.muni.cz/aktuality/studentska-vedecka-konference-2023},
   year = {2023}
}

TY  - CONF
ID  - 2408377
AU  - Biskupič, Jan - Vlčnovská, Marcela - Hložková, Jana - Scheer, Peter - Padrtová, Tereza - Opatřilová, Radka - Kanický, Viktor - Vaculovič, Tomáš - Kuchynka, Michaela
PY  - 2023
TI  - NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND TREATMENT OF ISCHEMIC STROKE
SN  - 9788028003234
KW  - Bioimaging
KW  - laser ablation
KW  - element distribution
UR  - https://www.pharm.muni.cz/aktuality/studentska-vedecka-konference-2023
N2  - Ischemic stroke (IS) was identified as the second most common cause of death worldwide in 2019 according to a survey [1]. A large percentage of patients remain with permanent consequences that can persist even fifteen years after the event [2]. This is also associated with economic impacts on healthcare and supportive services, which amounted to approximately 60 billion euros in the EU in 2017 [3]. The key to success is time. IS can already be precisely diagnosed nowadays. However, in each specific situation, there is a problem with detecting the onset of stroke, which is crucial for choosing the appropriate treatment and thus saving lives. Today’s commonly used medical scanning devices can only visualize clots with high erythrocyte content. Other forms of thrombi become very difficult to recognize [4]. Polyiodinated biodegradable nanoparticles (IoNPs) have the potential to solve this problem. The current preclinical phase of our project is focused on researching the pharmacokinetics of these potential IoNPs theranostics in the body. A unique method LA-ICP-MS is used to determine the IoNPs distribution. The study was supported by Grant Agency of Masaryk University – Excellent diploma thesis, MUNI/C/0002/2023.
ER  -

BISKUPIČ, Jan, Marcela VLČNOVSKÁ, Jana HLOŽKOVÁ, Peter SCHEER, Tereza PADRTOVÁ, Radka OPATŘILOVÁ, Viktor KANICKÝ, Tomáš VACULOVIČ and Michaela KUCHYNKA. NANOPARTICLES AS A NEW TOOL FOR THE DIAGNOSIS AND TREATMENT OF ISCHEMIC STROKE. In \textit{Student Scientific Conference MUNI Pharm}. 2023. ISBN~978-80-280-0323-4.

Detailed Information on Publication Record