Comparing the Efficacy of Digital and In-Person Weight Loss
Interventions for Patients with Obesity and Glycemic Disorders:
Evidence from a Randomized Non-Inferiority Trial

J 2024

Comparing the Efficacy of Digital and In-Person Weight Loss Interventions for Patients with Obesity and Glycemic Disorders: Evidence from a Randomized Non-Inferiority Trial

MORAVCOVA, Katarina, Marketa SOVOVA, Jaromir OZANA, Martina KARBANOVÁ, Jan KLASEK et. al.

Basic information

Original name

Comparing the Efficacy of Digital and In-Person Weight Loss Interventions for Patients with Obesity and Glycemic Disorders: Evidence from a Randomized Non-Inferiority Trial

Authors

MORAVCOVA, Katarina (203 Czech Republic), Marketa SOVOVA (203 Czech Republic), Jaromir OZANA (203 Czech Republic), Martina KARBANOVÁ (203 Czech Republic, belonging to the institution), Jan KLASEK (203 Czech Republic), Agnieszka Barbara KOLASINSKA (203 Czech Republic) and Eliska SOVOVA (203 Czech Republic)

Edition

Nutrients, Basel, MDPI, 2024, 2072-6643

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.900 in 2022

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3390/nu16101510

UT WoS

001231311000001

Keywords in English

obesity; digital therapeutics; lifestyle intervention; diabetes mellitus type 2; insulin resistance

Abstract

V originále

Digital weight loss interventions present a viable and cost-effective alternative to traditional therapy. However, further evidence is needed to establish the equal effectiveness of both approaches. This randomized controlled non-inferiority trial aimed to compare the effects of an intensive in-person weight loss intervention program with Vitadio digital therapy. One hundred patients with obesity and diagnosed with type 2 diabetes, prediabetes, or insulin resistance were enrolled and randomly assigned to one of the two treatment groups. Over a 6-month period, the control group received five in-person consultations with a physician who specialized in obesity treatment, a dietitian and/or a nutrition nurse, while the intervention group followed the digital program based on a multimodal therapeutic approach. The extent of weight loss was assessed and compared between the groups. Additionally, changes in body composition and metabolic parameters for the digital intervention group were analyzed. The study results demonstrated comparable effectiveness of both treatments for weight reduction. The positive effects of Vitadio were further evidenced by favorable changes in body composition and lipid metabolism and improved glycemic control in the intervention group. These findings suggest that Vitadio is an effective tool for assisting patients with managing obesity and preventing diabetes progression.

Citovat

MORAVCOVA, Katarina, Marketa SOVOVA, Jaromir OZANA, Martina KARBANOVÁ, Jan KLASEK, Agnieszka Barbara KOLASINSKA and Eliska SOVOVA. Comparing the Efficacy of Digital and In-Person Weight Loss Interventions for Patients with Obesity and Glycemic Disorders: Evidence from a Randomized Non-Inferiority Trial. Nutrients. Basel: MDPI, 2024, vol. 16, No 10, p. 1-13. ISSN 2072-6643. Available from: https://dx.doi.org/10.3390/nu16101510.

@article{2409338,
   author = {Moravcova, Katarina and Sovova, Marketa and Ozana, Jaromir and Karbanová, Martina and Klasek, Jan and Kolasinska, Agnieszka Barbara and Sovova, Eliska},
   article_location = {Basel},
   article_number = {10},
   doi = {http://dx.doi.org/10.3390/nu16101510},
   keywords = {obesity; digital therapeutics; lifestyle intervention; diabetes mellitus type 2; insulin resistance},
   language = {eng},
   issn = {2072-6643},
   journal = {Nutrients},
   title = {Comparing the Efficacy of Digital and In-Person Weight Loss Interventions for Patients with Obesity and Glycemic Disorders: Evidence from a Randomized Non-Inferiority Trial},
   url = {https://www.mdpi.com/2072-6643/16/10/1510},
   volume = {16},
   year = {2024}
}

TY  - JOUR
ID  - 2409338
AU  - Moravcova, Katarina - Sovova, Marketa - Ozana, Jaromir - Karbanová, Martina - Klasek, Jan - Kolasinska, Agnieszka Barbara - Sovova, Eliska
PY  - 2024
TI  - Comparing the Efficacy of Digital and In-Person Weight Loss Interventions for Patients with Obesity and Glycemic Disorders: Evidence from a Randomized Non-Inferiority Trial
JF  - Nutrients
VL  - 16
IS  - 10
SP  - 1-13
EP  - 1-13
PB  - MDPI
SN  - 20726643
KW  - obesity
KW  - digital therapeutics
KW  - lifestyle intervention
KW  - diabetes mellitus type 2
KW  - insulin resistance
UR  - https://www.mdpi.com/2072-6643/16/10/1510
N2  - Digital weight loss interventions present a viable and cost-effective alternative to traditional therapy. However, further evidence is needed to establish the equal effectiveness of both approaches. This randomized controlled non-inferiority trial aimed to compare the effects of an intensive in-person weight loss intervention program with Vitadio digital therapy. One hundred patients with obesity and diagnosed with type 2 diabetes, prediabetes, or insulin resistance were enrolled and randomly assigned to one of the two treatment groups. Over a 6-month period, the control group received five in-person consultations with a physician who specialized in obesity treatment, a dietitian and/or a nutrition nurse, while the intervention group followed the digital program based on a multimodal therapeutic approach. The extent of weight loss was assessed and compared between the groups. Additionally, changes in body composition and metabolic parameters for the digital intervention group were analyzed. The study results demonstrated comparable effectiveness of both treatments for weight reduction. The positive effects of Vitadio were further evidenced by favorable changes in body composition and lipid metabolism and improved glycemic control in the intervention group. These findings suggest that Vitadio is an effective tool for assisting patients with managing obesity and preventing diabetes progression.
ER  -

MORAVCOVA, Katarina, Marketa SOVOVA, Jaromir OZANA, Martina KARBANOVÁ, Jan KLASEK, Agnieszka Barbara KOLASINSKA and Eliska SOVOVA. Comparing the Efficacy of Digital and In-Person Weight Loss Interventions for Patients with Obesity and Glycemic Disorders: Evidence from a Randomized Non-Inferiority Trial. \textit{Nutrients}. Basel: MDPI, 2024, vol.~16, No~10, p.~1-13. ISSN~2072-6643. Available from: https://dx.doi.org/10.3390/nu16101510.

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