| MOTOLA, Martin, Jan CAPEK, Raul ZAZPE, Jana BACOVA, Ludek HROMADKO, Lenka BRUCKOVA, Siowwoon NG, Jiri HANDL, Zdenek SPOTZ, Petr KNOTEK, Kaushik BAISHYA, Pavlina MAJTNEROVA, Jan PRIKRYL, Hanna SOPHA, Tomas ROUSAR and Jan M MACAK. Thin TiO<sub>2</sub> Coatings by ALD Enhance the Cell Growth on TiO<sub>2</sub> Nanotubular and Flat Substrates. ACS APPLIED BIO MATERIALS. WASHINGTON: AMER CHEMICAL SOC, 2020, vol. 3, No 9, p. 6447-6456. ISSN 2576-6422. Available from: https://dx.doi.org/10.1021/acsabm.0c00871. |
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@article{2409839,
author = {Motola, Martin and Capek, Jan and Zazpe, Raul and Bacova, Jana and Hromadko, Ludek and Bruckova, Lenka and Ng, Siowwoon and Handl, Jiri and Spotz, Zdenek and Knotek, Petr and Baishya, Kaushik and Majtnerova, Pavlina and Prikryl, Jan and Sopha, Hanna and Rousar, Tomas and Macak, Jan M},
article_location = {WASHINGTON},
article_number = {9},
doi = {http://dx.doi.org/10.1021/acsabm.0c00871},
keywords = {TiO2 nanotube layers; Ti sheets; atomic layer deposition; coatings; cell growth},
language = {eng},
issn = {2576-6422},
journal = {ACS APPLIED BIO MATERIALS},
title = {Thin TiO<sub>2</sub> Coatings by ALD Enhance the Cell Growth on TiO<sub>2</sub> Nanotubular and Flat Substrates},
url = {https://pubs.acs.org/doi/10.1021/acsabm.0c00871},
volume = {3},
year = {2020}
}
TY - JOUR
ID - 2409839
AU - Motola, Martin - Capek, Jan - Zazpe, Raul - Bacova, Jana - Hromadko, Ludek - Bruckova, Lenka - Ng, Siowwoon - Handl, Jiri - Spotz, Zdenek - Knotek, Petr - Baishya, Kaushik - Majtnerova, Pavlina - Prikryl, Jan - Sopha, Hanna - Rousar, Tomas - Macak, Jan M
PY - 2020
TI - Thin TiO<sub>2</sub> Coatings by ALD Enhance the Cell Growth on TiO<sub>2</sub> Nanotubular and Flat Substrates
JF - ACS APPLIED BIO MATERIALS
VL - 3
IS - 9
SP - 6447-6456
EP - 6447-6456
PB - AMER CHEMICAL SOC
SN - 25766422
KW - TiO2 nanotube layers
KW - Ti sheets
KW - atomic layer deposition
KW - coatings
KW - cell growth
UR - https://pubs.acs.org/doi/10.1021/acsabm.0c00871
N2 - The present work exploits Ti sheets and TiO2 nanotube (TNT) layers and their surface modifications for the proliferation of different cells. Ti sheets with a native oxide layer, Ti sheets with a crystalline thermal oxide layer, and two kinds of TNT layers (prepared via electrochemical anodization) with a defined inner diameter of 12 and 15 nm were used as substrates. A part of the Ti sheets and the TNT layers was additionally coated by thin TiO2 coatings using atomic layer deposition (ALD). An increase in cell growth of WI-38 fibroblasts (>50%), MG-63 osteoblasts (>30%), and SH-SY5Y neuroblasts (>30%) was observed for all materials coated by five cycles ALD compared to their uncoated counterparts. The additional ALD TiO2 coatings changed the surface composition of all materials but preserved their original structure and protected them from unwanted crystallization and shape changes. The presented approach of mild surface modification by ALD has a significant effect on the materials biocompatibility and is promising toward application in implant materials.
ER -
MOTOLA, Martin, Jan CAPEK, Raul ZAZPE, Jana BACOVA, Ludek HROMADKO, Lenka BRUCKOVA, Siowwoon NG, Jiri HANDL, Zdenek SPOTZ, Petr KNOTEK, Kaushik BAISHYA, Pavlina MAJTNEROVA, Jan PRIKRYL, Hanna SOPHA, Tomas ROUSAR and Jan M MACAK. Thin TiO\&{}lt;sub\&{}gt;2\&{}lt;/sub\&{}gt; Coatings by ALD Enhance the Cell Growth on TiO\&{}lt;sub\&{}gt;2\&{}lt;/sub\&{}gt; Nanotubular and Flat Substrates. \textit{ACS APPLIED BIO MATERIALS}. WASHINGTON: AMER CHEMICAL SOC, 2020, vol.~3, No~9, p.~6447-6456. ISSN~2576-6422. Available from: https://dx.doi.org/10.1021/acsabm.0c00871.
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