Determination of PPAR gamma agonistic activity of mimulone and diplacone in nanoparticle formulations

NYKODÝMOVÁ, Daniela, Lenka MOLČANOVÁ, Jan KOTOUČEK, Josef MAŠEK and Jakub TREML. Determination of PPAR gamma agonistic activity of mimulone and diplacone in nanoparticle formulations. In PSE Trends in Natural Products 2024 Young Scientists' Meeting. 2024. ISBN 978-80-280-0559-7.

Basic information

• Original name: Determination of PPAR gamma agonistic activity of mimulone and diplacone in nanoparticle formulations
• Authors: NYKODÝMOVÁ, Daniela (203 Czech Republic, guarantor, belonging to the institution), Lenka MOLČANOVÁ (703 Slovakia, belonging to the institution), Jan KOTOUČEK (203 Czech Republic), Josef MAŠEK (203 Czech Republic) and Jakub TREML (203 Czech Republic, belonging to the institution).
• Edition: PSE Trends in Natural Products 2024 Young Scientists' Meeting, 2024.

Other information

• Original language: English
• Type of outcome: Presentations at conferences
• Field of Study: 30402 Technologies involving the manipulation of cells, tissues, organs or the whole organism
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• WWW: PSE 2024: Book of abstracts
• Organization unit: Faculty of Pharmacy
• ISBN: 978-80-280-0559-7
• Keywords in English: PPARγ; nanoparticles; flavanones

Abstract

The aim of this study was to determine whether geranylated flavanones from Paulownia tomentosa can affect glucose metabolism via activation of the PPARγ pathway in vitro, to compare the data for the compounds alone and the same compounds in different nanoparticles, and to determine the nanoparticle delivery system with the least possible loss of biological effect of the active compounds.

Links

• MUNI/A/1280/2021, interní kód MU: Name: Stanovení PPARg agonismu u vybraných přírodních látek v nanočásticových systémech

Investor: Masaryk University