APOSTOLOPOULOS, Vasileios, Petr BOHAC, Petr MARCIAN, Iva STANICZKOVÁ ZAMBO, Lukáš PAZOUREK, Michal MAHDAL, Jakub NERADIL, Tomas NAVRAT and Tomáš TOMÁŠ. ASO Author Reflections: The Effect of Local Adjuvants on Cortical Bone Following Intralesional Curettage of Bone Tumors. Annals of Surgical Oncology. New York: Springer, 2024, 2 pp. ISSN 1068-9265. Available from: https://dx.doi.org/10.1245/s10434-024-15473-9.
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Basic information
Original name ASO Author Reflections: The Effect of Local Adjuvants on Cortical Bone Following Intralesional Curettage of Bone Tumors
Authors APOSTOLOPOULOS, Vasileios, Petr BOHAC, Petr MARCIAN, Iva STANICZKOVÁ ZAMBO, Lukáš PAZOUREK, Michal MAHDAL, Jakub NERADIL, Tomas NAVRAT and Tomáš TOMÁŠ.
Edition Annals of Surgical Oncology, New York, Springer, 2024, 1068-9265.
Other information
Original language English
Type of outcome Article in a journal
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.700 in 2022
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1245/s10434-024-15473-9
UT WoS 001236806200002
Tags 14110112, 14110123
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 2/7/2024 08:51.
Abstract
The irregular shape of the tumor cavity in certain types of tumors poses a significant challenge in completely removing both microscopic and macroscopic tumor residues. Consequently, higher rates of local recurrence following tumor curettage have been recorded. To lower those rates, curettage should be supplemented with other local adjuvants. The objective of local adjuvant therapy is to eradicate any remaining viable tumor cells, ensuring complete removal while preserving the integrity of nearby healthy bone and surrounding soft tissue. Various treatment combinations are employed upon curettage for both benign and locally aggressive bone tumors. Despite the array of available treatment modalities, notable complication rates persisted, with postoperative fractures emerging as the most prevalent complication during follow-up periods. Thus far, no studies have comprehensively evaluated the effect of topical adjuvants on cortical bone after intralesional bone curettage by measuring density and hardness.
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