J 2024

ASO Author Reflections: The Effect of Local Adjuvants on Cortical Bone Following Intralesional Curettage of Bone Tumors

APOSTOLOPOULOS, Vasileios, Petr BOHAC, Petr MARCIAN, Iva STANICZKOVÁ ZAMBO, Lukáš PAZOUREK et. al.

Basic information

Original name

ASO Author Reflections: The Effect of Local Adjuvants on Cortical Bone Following Intralesional Curettage of Bone Tumors

Authors

APOSTOLOPOULOS, Vasileios (203 Czech Republic, belonging to the institution), Petr BOHAC (203 Czech Republic), Petr MARCIAN (203 Czech Republic), Iva STANICZKOVÁ ZAMBO (203 Czech Republic, belonging to the institution), Lukáš PAZOUREK (203 Czech Republic, belonging to the institution), Michal MAHDAL (203 Czech Republic, belonging to the institution), Jakub NERADIL (203 Czech Republic, belonging to the institution), Tomas NAVRAT (203 Czech Republic) and Tomáš TOMÁŠ (203 Czech Republic, belonging to the institution)

Edition

Annals of Surgical Oncology, New York, Springer, 2024, 1068-9265

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30212 Surgery

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.700 in 2022

Organization unit

Faculty of Medicine

UT WoS

001236806200002

Keywords in English

Intralesional Curettage; Bone Tumors; Local Adjuvants

Tags

International impact, Reviewed
Změněno: 31/10/2024 15:04, Mgr. Tereza Miškechová

Abstract

V originále

The irregular shape of the tumor cavity in certain types of tumors poses a significant challenge in completely removing both microscopic and macroscopic tumor residues. Consequently, higher rates of local recurrence following tumor curettage have been recorded. To lower those rates, curettage should be supplemented with other local adjuvants. The objective of local adjuvant therapy is to eradicate any remaining viable tumor cells, ensuring complete removal while preserving the integrity of nearby healthy bone and surrounding soft tissue. Various treatment combinations are employed upon curettage for both benign and locally aggressive bone tumors. Despite the array of available treatment modalities, notable complication rates persisted, with postoperative fractures emerging as the most prevalent complication during follow-up periods. Thus far, no studies have comprehensively evaluated the effect of topical adjuvants on cortical bone after intralesional bone curettage by measuring density and hardness.