LEINVEBER, Pavel, Josef HALAMEK, Karol CURILA, Frits PRINZEN, Jolana LIPOLDOVÁ, Magdalena MATEJKOVA, Radovan SMISEK, Filip PLESINGER, Andrej NAGY, Miroslav NOVÁK, Ivo VISCOR, Vlastimil VONDRA a Pavel JURAK. Ultra-high-frequency ECG volumetric and negative derivative epicardial ventricular electrical activation pattern. Nature Scientific Reports. Berlin: NATURE RESEARCH, 2024, roč. 14, č. 1, s. 1-11. ISSN 2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-024-55789-w. |
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@article{2417670, author = {Leinveber, Pavel and Halamek, Josef and Curila, Karol and Prinzen, Frits and Lipoldová, Jolana and Matejkova, Magdalena and Smisek, Radovan and Plesinger, Filip and Nagy, Andrej and Novák, Miroslav and Viscor, Ivo and Vondra, Vlastimil and Jurak, Pavel}, article_location = {Berlin}, article_number = {1}, doi = {http://dx.doi.org/10.1038/s41598-024-55789-w}, keywords = {ECG}, language = {eng}, issn = {2045-2322}, journal = {Nature Scientific Reports}, title = {Ultra-high-frequency ECG volumetric and negative derivative epicardial ventricular electrical activation pattern}, url = {https://www.nature.com/articles/s41598-024-55789-w}, volume = {14}, year = {2024} }
TY - JOUR ID - 2417670 AU - Leinveber, Pavel - Halamek, Josef - Curila, Karol - Prinzen, Frits - Lipoldová, Jolana - Matejkova, Magdalena - Smisek, Radovan - Plesinger, Filip - Nagy, Andrej - Novák, Miroslav - Viscor, Ivo - Vondra, Vlastimil - Jurak, Pavel PY - 2024 TI - Ultra-high-frequency ECG volumetric and negative derivative epicardial ventricular electrical activation pattern JF - Nature Scientific Reports VL - 14 IS - 1 SP - 1-11 EP - 1-11 PB - NATURE RESEARCH SN - 20452322 KW - ECG UR - https://www.nature.com/articles/s41598-024-55789-w N2 - From precordial ECG leads, the conventional determination of the negative derivative of the QRS complex (ND-ECG) assesses epicardial activation. Recently we showed that ultra-high-frequency electrocardiography (UHF-ECG) determines the activation of a larger volume of the ventricular wall. We aimed to combine these two methods to investigate the potential of volumetric and epicardial ventricular activation assessment and thereby determine the transmural activation sequence. We retrospectively analyzed 390 ECG records divided into three groups-healthy subjects with normal ECG, left bundle branch block (LBBB), and right bundle branch block (RBBB) patients. Then we created UHF-ECG and ND-ECG-derived depolarization maps and computed interventricular electrical dyssynchrony. Characteristic spatio-temporal differences were found between the volumetric UHF-ECG activation patterns and epicardial ND-ECG in the Normal, LBBB, and RBBB groups, despite the overall high correlations between both methods. Interventricular electrical dyssynchrony values assessed by the ND-ECG were consistently larger than values computed by the UHF-ECG method. Noninvasively obtained UHF-ECG and ND-ECG analyses describe different ventricular dyssynchrony and the general course of ventricular depolarization. Combining both methods based on standard 12-lead ECG electrode positions allows for a more detailed analysis of volumetric and epicardial ventricular electrical activation, including the assessment of the depolarization wave direction propagation in ventricles. ER -
LEINVEBER, Pavel, Josef HALAMEK, Karol CURILA, Frits PRINZEN, Jolana LIPOLDOVÁ, Magdalena MATEJKOVA, Radovan SMISEK, Filip PLESINGER, Andrej NAGY, Miroslav NOVÁK, Ivo VISCOR, Vlastimil VONDRA a Pavel JURAK. Ultra-high-frequency ECG volumetric and negative derivative epicardial ventricular electrical activation pattern. \textit{Nature Scientific Reports}. Berlin: NATURE RESEARCH, 2024, roč.~14, č.~1, s.~1-11. ISSN~2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-024-55789-w.
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